Skip to main content
Log in

2,3-Butanediol production from Jerusalem artichoke, Helianthus tuberosus, by Bacillus polymyxa ATCC 12 321. Optimization of k L a profile

  • Published:
Applied Microbiology and Biotechnology Aims and scope Submit manuscript

Summary

Optimization of d-(-)-2,3-butanediol production from the Jerusalem artichoke, Helianthus tuberosus, by Bacillus polymyxa ATCC 12 321 is described. The effects of initial sugar concentration and oxygen transfer rate were examined. The latter appears to be the most important parameter affecting the kinetics of the process. The best results (44 g·l-1 2,3-butanediol, productivity of 0.79 g·l-1·h-1) were obtained by setting an optimal k L a profile during batch culture.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Barrett EL, Collins EB, Hall BJ, Matoi H (1983) Production of 2,3-butylene glycol from whey by Klebsiella pneumoniae and Enterobacter aerogenes. J Dairy Sci 66:2507–2514

    Google Scholar 

  • Bu'Lock JD (1975) Acetone/butanol butanediol and other fermentations. Octagon Pap 2:5–19

    Google Scholar 

  • Fages J (1984) French patent pending

  • Hostettler F, Borel E, Deuel H (1951) Über die Reduktion der 3,5-Dinitrosalicylsäure durch Zucker. Helv Chim Acta 34:2133–2139

    Google Scholar 

  • Jansen NB, Flickinger MC, Tsao GT (1984a) Production of 2,3-butanediol from d-xylose by Klebsiella oxytoca ATCC 8724. Biotechnol Bioeng 26:362–369

    CAS  Google Scholar 

  • Jansen NB, Flickinger MC, Tsao GT (1984b) Application of bioenergetics to modelling the microbial conversion of d-xylose to 2,3-butanediol. Biotechnol Bioeng 26:573–582

    Google Scholar 

  • Kooi ER, Fulmer EI, Underkofler LA (1948) Production of 2,3-butanediol by fermentation of corn starch. Ind Eng Chem 40:1440–1445

    Google Scholar 

  • Ledingham GA, Neish AC (1954) Fermentative production of 2,3-butanediol. In: Hickey RJ, Underkofler LA (eds) Industrial fermentations, Vol 2, Chemical Publishing Co., New York, pp 27–93

    Google Scholar 

  • Long SK, Patrick R (1960) 2,3-Butylene glycol as a fermentation by-product from citrus wastes. Proc Fla State Hortic Soc 73:241–245

    Google Scholar 

  • Long SK, Patrick R (1963) The present status of the 2,3-butylene glycol fermentation. Adv Appl Microbiol 5:135–155

    Google Scholar 

  • Long SK, Patrick R (1965) Production of 2,3-butylene glycol from citrus wastes II. The Bacillus polymyxa fermentation. Appl Microbiol 13:973–976

    Google Scholar 

  • Murphy D, Stranks DW (1951) The production of 2,3-butanediol from sulphite waste liquor. Can J Technol 29:413–420

    Google Scholar 

  • Sablayrolles JM (1982) Fermentation butanediolique par Aerobacter aerogenes NRRL B 199. Thèse de Docteur-Ingénieur, INSA Toulouse

  • Simpson FJ, Stranks DW (1951) Production and properties of 2,3-butanediol XXXIV. Some factors affecting the fermentation of beet molasses by Bacillus polymyxa. Can J Technol 29:87–97

    Google Scholar 

  • Speckman RA, Collins EB (1982) Microbial production of 2,3-butylene glycol from cheese whey. Appl Environ Microbiol 43:1216–1218

    Google Scholar 

  • Taylor MB, Juni E (1958) Mechanisms of formation of stereoisomers of 2,3-butanediol during microbial fermentation on sugars. Nature 18:1389–1390

    Google Scholar 

  • Wilhelm JL, Fages J (1984) European patent no. 162 771

  • Willets A (1985) Butane 2,3-diol production by immobilized Aeromonas hydrophila. Biotechnol Lett 7:261–266

    Google Scholar 

  • Yu EKC, Saddler JN (1982) Enhanced production of 2,3-butanediol by Klebsiella pneumoniae grown at high sugar concengration in the presence of acetic acid. Appl Environ Microbiol 44:777–784

    Google Scholar 

  • Yu EKC, Saddler JN (1983) Fed batch approach to production of 2,3-butanediol by Klebsiella pneumoniae grown on high substrate concentrations. Appl Environ Microbiol 46:630–635

    Google Scholar 

  • Yu EKC, Deschatelets L, Tan LUL, Saddler JN (1985) A simple method for xylanase preparation used for the hydrolysis and fermentation of hemicellulose to butanediol. Biotechnol Lett 7:425–430

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fages, J., Mulard, D., Rouquet, JJ. et al. 2,3-Butanediol production from Jerusalem artichoke, Helianthus tuberosus, by Bacillus polymyxa ATCC 12 321. Optimization of k L a profile. Appl Microbiol Biotechnol 25, 197–202 (1986). https://doi.org/10.1007/BF00253648

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00253648

Keywords

Navigation