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Extraosseous localization of 99mTc-MDP in ganglioneuroblastoma

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Abstract

A 21/2-year-old boy with a posterior mediastinal ganglioneuroblastoma was evaluated by bone scintigraphy using 99mTc-MDP and showed a marked increased uptake in the tumor mass. Although a routine chest X-ray and body CT scan failed to demonstrate calcification, X-ray examination of the removed tumor specimen revealed small scattered calcification. The proposed mechanisms of the radiopharmaceutical localization in benign and malignant tumors other than calcification/mineralization are discussed. Regardless of the mechanism, localization of a bone scanning agent in a tumor provides a rapid, simple, and noninvasive means of demonstrating tumor size, configuration, and the relation of the surrounding structures to the tumor.

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Authors and Affiliations

  1. Veterans Administration Medical Center, University of Kentucky Medical Center, Lexington, Kentucky

    Wei-Jen Shih, Frank H. DeLand, Peggy A. Domstad & Edward H. Johnston

  2. Orlando Regional Medical Center, Orlando, Florida

    Wei-Jen Shih, Frank H. DeLand, Peggy A. Domstad & Edward H. Johnston

Authors
  1. Wei-Jen Shih
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  2. Frank H. DeLand
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  3. Peggy A. Domstad
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  4. Edward H. Johnston
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Shih, WJ., DeLand, F.H., Domstad, P.A. et al. Extraosseous localization of 99mTc-MDP in ganglioneuroblastoma. Eur J Nucl Med 7, 336–338 (1982). https://doi.org/10.1007/BF00253434

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  • DOI: https://doi.org/10.1007/BF00253434

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