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The preparation and characterisation of 111In-labelled 791T/36 monoclonal antibody for tumour immunoscintigraphy

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Abstract

The anti-human tumour monoclonal antibody 791T/36 was conjugated to the cyclic dianhydride of DTPA and radio-labelled with 111In. The labelling method proved to be both simple and reliable and would be suitable for routine clinical use. Subsequent characterisation of this radio-pharmaceutical in vitro and in tumour-bearing hosts gave a strong indication as to its suitability for clinical tumour localisation studies.

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Perkins, A.C., Pimm, M.V. & Birch, M.K. The preparation and characterisation of 111In-labelled 791T/36 monoclonal antibody for tumour immunoscintigraphy. Eur J Nucl Med 10, 296–301 (1985). https://doi.org/10.1007/BF00251299

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  • DOI: https://doi.org/10.1007/BF00251299

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