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Fructose metabolism in Zymomonas mobilis

  • Applied Microbiology
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Summary

In the metabolism of fructose by Zymomonas, the ethanol yield is decreased due to the formation of dihydroxyacetone, mannitol and glycerol. The reduction of fructose to mannitol by an NADPH-dependent mannitol dehydrogenase is apparently coupled to the oxidation of glucose-6-phosphate by glucose-6-phosphate dehydrogenase, which exhibits higher activity with NADP than with NAD as cofactor. The relatively low cell yield on fructose can partly be explained by the loss of ATP in the formation of dihydroxyacetone and glycerol and partly by the toxic effect of dihydroxyacetone and acetaldehyde on the growth of the organism.

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Authors and Affiliations

  1. Biotechnical Laboratory, VTT, Tietotie 2, SF-02150, Espoo, Finland

    Liisa Viikari

  2. The Finnish State Alcohol Company (Alko Ltd.), POB 350, SF-00101, Helsinki, Finland

    Matti Korhola

Authors
  1. Liisa Viikari
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  2. Matti Korhola
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Viikari, L., Korhola, M. Fructose metabolism in Zymomonas mobilis . Appl Microbiol Biotechnol 24, 471–476 (1986). https://doi.org/10.1007/BF00250326

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  • DOI: https://doi.org/10.1007/BF00250326

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