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Modulation of lemniscal input during conditioned arm movements in the monkey

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Summary

Modulation of sensory transmission in the lemniscal system was investigated in 2 monkeys trained to perform a simple elbow flexion in response to an auditory cue. Evoked responses to peripheral stimulation were recorded in the medial lemniscus, sensory thalamus (ventral posterior lateral nucleus, caudal division, VPLc) and somatosensory cortex. Simultaneous recordings were made from the cortex and either the medial lemniscus or VPLc. At all recording sites, evoked responses to natural (air puff) or electrical, percutaneous stimulation were depressed prior to and during active movement. The time course of the depression was similar at all three levels; the magnitude of the decrease during movement was most pronounced at the cortical level. Cortical evoked responses to central stimulation of effective sites in either the medial lemniscus or VPLc were decreased during, but not before, the onset of movement. The decrease was less than that seen for peripheral evoked potentials. Passive movement of the forearm significantly decreased all but the lemniscal evoked potential. The results indicate that there is a centrally mediated suppression of somatosensory transmission prior to, and during movement, occurring at the level of the first relay, the dorsal column nuclei. During movement, reafferent signals from the moving arm decrease transmission at the thalamocortical level.

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References

  • Abbruzzese G, Ratto F, Favale E, Abbruzzese M (1981) Proprioceptive modulation of somatosensory evoked potentials during active or passive finger movements in man. J Neurol Neurosurg Psychiat 44: 942–949

    Google Scholar 

  • Bentivoglio M, Rustioni A (1986) Corticospinal neurons with branching axons to the dorsal column nuclei in the monkey. J Comp Neurol 253: 260–276

    Google Scholar 

  • Biedenbach MA, Jabbur SJ, Towe AL (1971) Afferent inhibition in the cuneate nucleus of the rhesus monkey. Brain Res 27: 179–183

    Google Scholar 

  • Bioulac B, Lamarre Y (1979) Activity of postcentral cortical neurons of the monkey during conditioned movements of a deafferented limb. Brain Res 172: 427–437

    Google Scholar 

  • Cesa-Bianchi MG, Sotgiu ML (1969) Control by brain stem reticular formation of sensory transmission in Burdach nucleus. Analysis of single units. Brain Res 13: 129–139

    Google Scholar 

  • Chapin JK, Woodward DJ (1981) Modulation of sensory responsiveness of single somatosensory cortical cells during movement and arousal behaviors. Exp Neurol 72: 164–178

    Google Scholar 

  • Chapin JK, Woodward DJ (1982) Somatic sensory transmission to the cortex during movement: gating of single cell responses to touch. Exp Neurol 78: 654–669

    Google Scholar 

  • Chapman CE, Bushnell MC, Miron D, Duncan GH, Lund JP (1987) Sensory perception during movement in man. Exp Brain Res 68: 516–524

    Google Scholar 

  • Chapman CE, Jiang W, Lamarre Y (1986) Modulation of lemniscal input during movement in the monkey. Proc Int Union Physiol Sci 16: 204

    Google Scholar 

  • Chapman CE, Rispal-Padel L, Parent M-T, Lamarre Y (1984) Gating of lemniscal input at thalamic and cortical levels during conditioned arm movements in the monkey. Abstr Soc Neurosci 10: 735

    Google Scholar 

  • Chapman CE, Spidalieri G, Lamarre Y (1986) Activity of dentate neurons during arm movements triggered by visual, auditory and somesthetic stimuli in the monkey. J Neurophysiol 55: 203–226

    Google Scholar 

  • Cheema S, Rustioni A, Whitsel BL (1985) Sensorimotor cortical projections to the primate cuneate nucleus. J Comp Neurol 240: 196–211

    Google Scholar 

  • Cohen LG, Starr A (1987) Localization, timing and specificity of gating of somatosensory evoked potentials during active movement in man. Brain 110: 451–467

    Google Scholar 

  • Cole JD, Gordon G (1983) Timing of corticofugal actions on the gracile and cuneate nuclei of the cat. J Physiol (Lond) 340: 139–152

    Google Scholar 

  • Coquery JM (1978) Role of active movement in control of afferent input from skin in cat and man. In: Gordon G (ed) Active touch. Pergamon Press, Oxford, pp 161–169

    Google Scholar 

  • Coquery JM, Coulmance M, Leron MC (1972) Modifications des potentiels évoqués corticaux somesthésiques durant des mouvements actifs et passifs chez l'homme. Electroenceph Clin Neurophysiol 33: 269–276

    Google Scholar 

  • Coquery JM, Malcuit G, Coulmance M (1971) Altérations de la perception d'un stimulus somesthésique durant un mouvement volontaire. C R Soc Biol (Paris) 165: 1946–1951

    Google Scholar 

  • Coquery JM, Vitton N (1972) Altérations des potentiels évoqués sur le cortex somesthésique du chat durant un mouvement conditionné. Physiol Behav 8: 963–967

    Google Scholar 

  • Coulter JD (1974) Sensory transmission through lemniscal pathway during voluntary movement in the cat. J Neurophysiol 37: 831–845

    Google Scholar 

  • Dyhre-Poulson P (1978) Perception of tactile stimuli before ballistic and during tracking movements. In: Gordon G (ed) Active touch. Pergamon Press, Oxford, pp 171–176

    Google Scholar 

  • Evarts EV (1966) Pyramidal tract activity associated with a conditioned hand movement in the monkey. J Neurophysiol 29: 1011–1027

    Google Scholar 

  • Evarts EV (1972) Contrasts between activity of precentral and postcentral neurons of cerebral cortex during movement in the monkey. Brain Res 40: 25–31

    Google Scholar 

  • Evarts EV (1974) Precentral and postcentral cortical activity in association with visually triggered movement. J Neurophysiol 37: 373–381

    Google Scholar 

  • Fromm C, Evarts EV (1982). Pyramidal tract neurons in somatosensory cortex: central and peripheral inputs during voluntary movement. Brain Res 238: 186–191

    Google Scholar 

  • Ghez C, Lenzi GL (1971) Modulation of sensory transmission in cat lemniscal system during voluntary movement. Pflügers Arch 323: 273–278

    Google Scholar 

  • Ghez C, Pisa M (1972) Inhibition of afferent transmission in cuneate nucleus during voluntary movement in the cat. Brain Res 40: 145–151

    Google Scholar 

  • Giblin DR (1964) Somatosensory evoked potentials in healthy subjects and in patients with lesions of the nervous system. Ann NY Acad Sci 112: 93–142

    Google Scholar 

  • Giuffrida R, Sanderson P, Sapienza S (1985) Effect of microstimulation of movement-evoking cortical foci on the activity of neurons on the dorsal column nuclei. Somatosens Res 2: 237–247

    Google Scholar 

  • Hyvärinen J, Poranen A, Jokinen Y (1980) Influence of attentive behavior on neuronal responses to vibration in primary somatosensory cortex of the monkey. J Neurophysiol 43: 870–883

    Google Scholar 

  • Jiang W, Lamarre Y, Chapman CE (1986) Modulation of somatosensory input to sensory cortex produced by intracortical microstimulation of motor cortex in the monkey. Abstr Soc Neurosci 12: 259

    Google Scholar 

  • Jones EG (1984) Organization of the thalamocortical complex and its relation to sensory processes. In: Darian-Smith I (ed) Handbook of physiology, Sect I, Vol III. American Physiological Society, Washington, pp 149–212

    Google Scholar 

  • Jones EG, Coulter JD, Hendry SHC (1978) Intracortical connectivity of architectonic fields in the somatic sensory, motor and parietal cortex of monkeys. J Comp Neurol 181: 291–348

    Google Scholar 

  • Jones EG, Wise SP (1977) Size, laminar and columnar distribution of efferent cells in the sensory-motor cortex of monkeys. J Comp Neurol 175: 391–438

    Google Scholar 

  • Lamarre Y, Busby L, Spidalieri G (1983) Fast ballistic arm movements triggered by visual, auditory and somesthetic stimuli in the monkey. I. Activity of precentral cortical neurons. J Neurophysiol 50: 1343–1357

    Google Scholar 

  • Lamarre Y, Chapman CE (1986) Comparative timing in cortical and cerebellar structures during a simple arm movement in the monkey. Exp Brain Res Suppl 15: 14–27

    Google Scholar 

  • Lamarre Y, Joffroy AF, Filion M, Bouchoux R (1970) A stereotaxic method for repeated sessions of central unit recording in the paralysed or moving animal. Rev Can Biol 29: 371–376

    Google Scholar 

  • Lamarre Y, Spidalieri G, Lund JP (1981) Patterns of muscular and motor cortical activity during a simple arm movement in the monkey. Can J Physiol Pharmacol 59: 748–756

    Google Scholar 

  • Lamb GD (1983) Tactile discrimination of textured surfaces: psychophysical performance measurements in humans. J Physiol (Lond) 338: 551–565

    Google Scholar 

  • Nelson RJ (1984) Responsiveness of monkey primary somatosensory cortical neurons to peripheral stimulation depends on “motor-set”. Brain Res 304: 143–148

    Google Scholar 

  • Papakostopoulos D, Cooper R, Crow HJ (1975) Inhibition of cortical evoked potentials and sensation by self-initiated movement in man. Nature 258: 321–324

    Google Scholar 

  • Poranen A, Hyvärinen J (1982) Effects of attention on multiunit responses to vibration in the somatosensory regions of the monkey's brain. Electroenceph Clin Neurophysiol 53: 525–537

    Google Scholar 

  • Rushton DN, Rothwell JC, Craggs MD (1981) Gating of somatosensory evoked potentials during different kinds of movement in man. Brain 104: 465–491

    Google Scholar 

  • Soso MJ, Fetz EE (1980) Responses of identified cells in postcentral cortex of awake monkeys during comparable active and passive joint movements. J Neurophysiol 43: 1090–1110

    Google Scholar 

  • Tsumoto T, Nakamura S, Iwama K (1975) Pyramidal tract control over cutaneous and kinesthetic sensory transmission in the cat thalamus. Exp Brain Res 22: 281–294

    Google Scholar 

  • Vogt BA, Pandya DW (1977) Corticocortical connections of somatic sensory cortex (areas 3, 1 and 2) in the rhesus monkey. J Comp Neurol 177: 179–191

    Google Scholar 

  • Walsh JT, Cordeau JP (1965) Responsiveness in the visual system during various phases of sleep and waking. Exp Neurol 11: 80–103

    Google Scholar 

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Authors and Affiliations

  1. Centre de Recherche en Sciences Neurologiques, Station A, PO Box 6128, HC3 3J7, Montréal, Québec, Canada

    C. E. Chapman, W. Jiang & Y. Lamarre

  2. Ecole de Réadaptation, Station A, PO Box 6128, HC3 3J7, Montréal, Québec, Canada

    C. E. Chapman

  3. Département de Physiologie, Université de Montréal, Station A, PO Box 6128, HC3 3J7, Montréal, Québec, Canada

    Y. Lamarre

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  1. C. E. Chapman
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  2. W. Jiang
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  3. Y. Lamarre
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Chapman, C.E., Jiang, W. & Lamarre, Y. Modulation of lemniscal input during conditioned arm movements in the monkey. Exp Brain Res 72, 316–334 (1988). https://doi.org/10.1007/BF00250254

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  • DOI: https://doi.org/10.1007/BF00250254

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