Summary
Recordings from the visual cortex of anaesthetized monkeys taken with a 30-fold multimicroelectrode demonstrate that the neuronal variability, defined as the change in response strength over time spans of a few seconds to several minutes, is highly correlated within groups of neurones. Several such groups exhibiting independent variability between groups, coexist within the area recorded. This within-group covariance suggests that a major part of neuronal variability is due not to a noise process in the cells, but rather to additional inputs to the neurones, which are not under control of the experimenter.
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References
Bach M (1981) Untersuchungen zur Wechselwirkung zwischen Nervenzellen im visuellen Cortex mit Vielfach-Mikroelektroden. PhD-Thesis, Freiburg
Bloom FE (1981) Chemical signaling and cortical circuitry: integrative aspects. In: Schmitt FO, Worden FG, Adelmann G, Dennis SG (eds) The organisation of the cerebral cortex. MIT Press Cambridge (Mass), pp 359–370
Bullock TH (1970) The reliability of eurones. J Gen Physiol 55: 565–584
Burns BD (1968) The uncertain nervous system. Arnold E, London
Cooley WW, Lohnes PR (1971) Multivariate data analysis. John Wiley & Sons, New York
Dammasch IE, Wagner GP (1984) On the properties of randomly connected McCulloch-Pitts networks: differences between input-constant and input-variant networks. Cybern Syst 15: 91–117
Doty RW (1980) Non geniculate afferents to striate cortex in macaques. Exp Brain Res 41: A10–11
Everitt B (1974) Cluster analysis. Heineman Educational Books Ltd, London
Hammersley JM, Handscomb DC (1979) Monte Carlo methods. Chapman and Hall, London
Holden AV, Ramadan SM (1980) Identification of endogenous and exogenous activity in a molluscan neurones by spike train analysis. Biol Cybern 37: 107–114
Krüger J, Bach M (1981) Simultaneous recording with 30 microelectrodes in monkey visual cortex. Exp Brain Res 41: 191–194
Krüger J, Bach M (1982) Independent systems of orientation columns in upper and lower layers of monkey visual cortex. Neurosci Lett 31: 225–230
Krüger J, Fischer B (1983) Colour columns and colour areas. In: Mollon JD, Sharpe LT (eds) Colour vision. Academic Press, London
Levine MW (1980) Firing rates of a retinal neurone are not predictable from interspike interval statistics. Biophys J 30: 9–25
McCulloch WS, Pitts WH (1943) A logical calculus of ideas immanent in nervous activity. Bull Math Biophys 5: 115–133
Moore GP, Segundo JP, Perkel DH, Levitan H (1970) Statistical signs of synaptic interactions in neurones. Biophys J 10: 876–900
Perkel DH, Gerstein GL, Moore GP (1967) Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains. Biophys J 7: 419–440
Rollet B, Bartram M (1976) Einführung in die hierarchische Clusteranalyse für Psychologen, Pädagogen und Soziologen. Ernst Klett Verlag, Stuttgart
Rose D (1979) An analysis of the variability of unit activity in the cat's visual cortex. Exp Brain Res 37: 595–604
Rosen R (1973) The use of deterministic or probabilistic models (discussion). In: Brazier MAB, Walter DO, Schneider D (eds) Neural modeling. Brain Information Service/Brain Research Institute, UCLA, Los Angeles
Schiller PH, Finlay BL, Volman SF (1976) Short-term response variability of macaque monkey striate neurones. Brain Res 105: 347–349
Sherry CJ, Klemm WR (1980) The statistical relationship between the “entropy” of a neuronal signal and its variability. J Neurosci 11: 109–113
Stein RB (1967) Some models of neuronal variability. Biophys J 7: 37–68
Überla K (1968) Faktorenanalyse. Springer, Berlin Heidelberg New York
Werner G, Mountcastle VB (1963) The variability of central neural activity in a sensory system and its implication for the central reflection of sensory events. J Neurophysiol 32: 727–742
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Supported by the Deutsche Forschungsgemeinschaft, Sonderforschungsbereich 70 “Hirnforschung und Sinnesphysiologie”
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Bach, M., Krüger, J. Correlated neuronal variability in monkey visual cortex revealed by a multi-microelectrode. Exp Brain Res 61, 451–456 (1986). https://doi.org/10.1007/BF00237570
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DOI: https://doi.org/10.1007/BF00237570