Summary
Brief pulses of Laser emitted radiant heat were used to induce cutaneous painful sensations in human volunteers. Accurate timing of the stimuli permitted recording of scalp averaged evoked potentials. A late negative-positive component of the EP which correlated in amplitude with the subjective sensation was abserved in four subjects. The latency of this component (130–160 msec) correlated with stimulus intensity.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Barret, G., Halliday, A.M., Halliday, E., Rudolf, N. de M.: The later components of the somatosen sory evoked response and the P300 in a threshold detection task. Paper delivered at the International Symposium on Cerebral Evoked Potentials in Man, Brussels, April 1974
Burgess, P.R., Perl, E.R.: Cutaneous mechanoreceptors and nociceptors. In: Handbook of Sensory Physiology, Vol. 2: Somatosensory System, (ed A. Iggo). Berlin-Heidelberg-New York: Springer 1974
Chatrian, G.E., Canfield, R.C., Knauss, T.A., Lettich, E.: Cerebral responses to electrical tooth pulp stimulation in man. Neurology (Minneap.) 25, 745–757 (1975)
Chin, J.H., Domino, E.F.: Effect of morphine on brain potentials evoked by stimulation of the tooth pulp of the dog. J. Pharmacol. exp. Ther. 132, 76–86 (1971)
Duclaux, R., Franzen, O., Chatt, A.B., Kenshalo, D.R., Stowell, H.: Responses recorded from human scalp evoked by cutaneous thermal stimulation. Brain Res. 78, 279–290 (1974)
Franzen, O., Offenloch, K.: Evoked response correlates of psychophysical magnitude estimates of tactile stimulation in man. Exp. Brain Res. 8, 1–18 (1969)
Goff, W.R., Matsumiya, Y., Allison, T., Goff, G.D.: Cross-modality comparisons of averaged evoked potentials. In: Averaged Evoked Potentials: Methods, Results and Evaluations. (eds. E. Donchin, D.B. Lindsley). Washington, D.C.: National Aeronautical and Space Administration 1969
Mor, J., Carmon, A.: Laser emitted radiant heat for pain research. Pain 1, 233–237 (1975)
Schmidt, J.: Die Beeinflussung der langsamen Hirnrindenpotentiale des Menschen nach elektrischer Zahnreizung durch Analgetika. Acta biol. med. germ. 24, 361–368 (1970)
Soto-Moyana, R., Hayser, D., Avramidis, E.: Evoked responses of an anterior area of the rabbit cortex to dental stimulation. C.R. Soc. Biol. (Paris) 160, 1387–1389 (1966)
Stellar, S., Polanyi, T.G., Bredemeir, H.C.: Lasers in surgery. In: Laser Applications in Medicine and Biology, Vol. 2 (ed. M.L. Wolbarsht). New York: Plenum Press 1973
Van Hassel, H.J., Biendenbach, M.A., Brown, A.C.: Cortical potentials evoked by tooth pulp stimulation in Rhesus monkeys. Arch. oral. Biol. 17, 1059–1066 (1972)
Uttal, W.R., Cook, L.: Systematics of the evoked somatosensory cortical potential: A psychophysical-electrophysiological comparison. Ann. N.Y. Acad. Sci. 112, 60–80 (1964)
Author information
Authors and Affiliations
Additional information
This study was supported by a David Rose Grant.
Rights and permissions
About this article
Cite this article
Carmon, A., Mor, J. & Goldberg, J. Evoked cerebral responses to noxious thermal stimuli in humans. Exp Brain Res 25, 103–107 (1976). https://doi.org/10.1007/BF00237330
Issue Date:
DOI: https://doi.org/10.1007/BF00237330