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Autoradiographic localization of3H-GABA and3H-muscimol binding in rat cerebellar cultures

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Autoradiographic studies were conducted on the binding of3H-GABA and3H-muscimol in cultures of rat cerebellum. Binding sites for both substances were observed on many cerebellar neurones, such as Purkinje cells and interneurones, but not on glial cells. Binding of3H-GABA and3H-muscimol was inhibited by unlabelled GABA and by the GABA antagonist bicuculline.

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Hösli, E., Hösli, L. Autoradiographic localization of3H-GABA and3H-muscimol binding in rat cerebellar cultures. Exp Brain Res 38, 241–243 (1980). https://doi.org/10.1007/BF00236746

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  • DOI: https://doi.org/10.1007/BF00236746

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