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Morphological investigations on follicular atresia in canine ovaries

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Summary

Morphologically, canine ovaries show two types of regression pattern in secondary follicles. In type A necrotic changes of the oocytes and the zona pellucida dominate, whereas in type B degeneration, necrobiosis and necrosis of the granulosa prevail. The atretic course of type B regression results in a pseudoantrum and leads, by pseudogrowth, to a structure imitating tertiary follicles. In both type A and type B regression, four consecutive stages of atresia are distinguished by light- and electron microscopy.

True tertiary follicles display only one regression pattern which resembles type B of secondary follicles. Early, advanced, late, and terminal stages of atresia are again described.

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References

  • Andersen AC, Simpson ME (1973) The ovary and the reproductive cycle of the dog (Beagle). Geron-X, Inc Los Altos, California

    Google Scholar 

  • Brand A, De Jong WHR (1973) Qualitative and quantitative micromorphological investigations of the tertiary follicle population during the oestrous cycle in the sheep. J Reprod Fertil 33:431–439

    CAS  Google Scholar 

  • Burkl W, Thiel-Bartosch F (1967) Elektronenmikroskopische Untersuchungen über die Granulosa atresierender Tertiär-Follikel bei der Ratte. Arch Gynäkol 204:238–250

    Google Scholar 

  • Byskov AG (1974) Cell kinetic studies of follicular atresia in the mouse ovary. J Reprod Fertil 37:277–285

    Google Scholar 

  • Byskov AG (1978) Atresia. In: Midgley AR, Sadler WA (eds) Ovarian follicular development and function. Raven Press, New York, pp 41–57

    Google Scholar 

  • Hay MF, Cran DG, Moor RM (1976) Structural changes occurring during atresia in sheep ovarian follicles. Cell Tissue Res 169:515–529

    Google Scholar 

  • Himelstein-Braw R, Byskov AG, Peters H, Faber M (1976) Follicular atresia in the infant human ovary. J Reprod Fertil 46:55–59

    Google Scholar 

  • Ingram DL (1962) Atresia. In: Zuckerman S (ed) The ovary Vol. 1. Academic Press, New York London, pp 247–273

    Google Scholar 

  • Knigge KM. Leathem JH (1956) Growth and atresia of follicles in the ovary of the hamster. Anat Rec 124:680–707

    Google Scholar 

  • Langmann J, Cardell EL (1978) Ultrastructural observations on FUdR-induced cell death and subsequent elimination of cell debris. Teratology 17:229–235

    Google Scholar 

  • Müller E (1955) Der Zelltod. In: Büchner F, Letterer E, Roulet F (eds) Handbuch der Allgemeinen Pathologie Vol 2/1. Springer, Berlin Göttingen Heidelberg, pp 613–679

    Google Scholar 

  • Oakberg EF (1979) Follicular growth and atresia in the mouse. In vitro 15:41–49

    Google Scholar 

  • O'Shea JD, Hay MF, Cran DG (1978) Ultrastructural changes in the theca during follicular atresia in sheep. J Reprod Fertil 54:183–187

    Google Scholar 

  • Peluso JJ, Steger RW, Hafez ESE (1977) Sequential changes associated with the degeneration of preovulatory follicles. J Reprod Fertil 49:215–218

    Google Scholar 

  • Peters H (1978) Some aspects of early follicular development. In: Midgley AR, Sadler LA (eds) Ovarian follicular development and function. Raven Press, New York, pp 1–13

    Google Scholar 

  • Richardson KC, Jarrett L, Finke EH (1960) Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol 35:313–323

    CAS  PubMed  Google Scholar 

  • Robbins SL, Angell M (1976) Basic Pathology. W B Saunders Co, Philadelphia London Toronto, pp 3–30

    Google Scholar 

  • Trump BF, Ginn FL (1969) The pathogenesis of subcellular reaction to lethal injury. In: Bajusz E, Jasmin G (eds) Methods and achievements in experimental pathology. S Karger AG, Basel, pp 1–29

    Google Scholar 

  • Vazquez-Nin GH, Sotelo JR (1967) Electron microscope study of the atretic oocyte of the rat. Z Zellforsch 80:518–533

    Google Scholar 

  • Watzka M (1957) Das Ovarium. In: Möllendorff W v, Bargmann W (eds) Handbuch der mikroskopischen Anatomie. Weibliche Genitalorgane. Vol 7/3. Springer, Berlin, pp 29–52

    Google Scholar 

  • Weakley BS (1966) Electron microscopy of the oocyte and granulosa cells in the developing ovarian follicles of the golden hamster (Mesocricetus auratus). J Anat 100:503–534

    Google Scholar 

Download references

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  1. Abt. für Klinische Morphologie, Universität Ulm, Postfach 4066, D-7900, Ulm, Federal Republic of Germany

    Katharina Spanel-Borowski

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  1. Katharina Spanel-Borowski
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Spanel-Borowski, K. Morphological investigations on follicular atresia in canine ovaries. Cell Tissue Res. 214, 155–168 (1981). https://doi.org/10.1007/BF00235153

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  • DOI: https://doi.org/10.1007/BF00235153

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