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Brain stimulation-induced changes of phonation in the squirrel monkey

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Summary

In 11 squirrel monkeys (Saimiri sciureus), the brain stem was systematically explored with electrical brain stimulation for sites affecting the acoustic structure of ongoing vocalization. Vocalization was elicited by electrical stimulation of different brain structures. A severe deterioration of the acoustical structure of vocalization was obtained during stimulation of the caudoventral part of the periaqueductal grey, lateral parabrachial area, corticobulbar tract, nucl. ambiguus and surrounding reticular formation, facial nucleus, hypoglossal nucleus, solitary tract nucleus and along the fibres crossing the midline at the level of the hypoglossal nucleus. It is suggested that these structures are part of, or at least have direct access to, the motor coordination mechanism of phonation. Complete inhibition of phonation was obtained from the raphe and raphe-near reticular formation.

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Abbreviations

Ab:

nucl ambiguus

APt:

area praetectalis

BC:

brachium conjunctivum

BP:

brachium pontis

Cb:

cerebellum

CC:

corpus callosum

Cd:

nucl. caudatus

Cf:

nucl. cuneiformis

Cel:

nucl. centralis lateralis

Cl:

claustrum

CM:

centrum medianum

Cn:

nucl. cuneatus

Co:

nucl. cochlearis

CoI:

colliculus inferior

CoS:

colliculus superior

CP:

commissura posterior

CPf:

cortex piriformis

CRf:

corpus restiforme

CSL:

nucl. centralis superior lateralis thalami

CT:

corpus trapezoideum

DBC:

decussatio brachii conjunctivi

DG:

nucl. dorsalis tegmenti (Gudden)

DLM:

decussatio lemnisci medialis

DPy:

decussatio pyramidum

DR:

nucl. dorsalis raphae

DV:

nucl. dorsalis n. vagi

DIV:

decussatio n. trochlearis

EP:

epiphysis

FC:

funiculus cuneatus

FL:

funiculus lateralis

FLM:

fasciculus longitudinalis medialis

FRM:

formatio reticularis myelencephali

FRP:

formatio reticularis pontis

FRPc:

formatio reticularis pontis caudalis

FRPo:

formatio reticularis pontis oralis

FRTM:

formatio reticularis mesencephali

FV:

funiculus ventralis

G:

nucl. gracilis

GC:

substantia grisea centralis (periaqueductal grey)

GL:

nucl. geniculatus lateralis

GM:

nucl. geniculatus medialis

GP:

globus pallidus

GPM:

griseum periventriculare mesencephali

GPo:

griseum pontis

Hip:

hippocampus

HL:

nucl. habenularis lateralis

H:

habenula

IP:

nucl. interpeduncularis

LC:

locus coeruleus

LD:

nucl. lateralis dorsalis thalami

Lim:

nucl. limitans

LLd:

nucl. lemnisci lateralis, pars dorsalis

LLv:

nucl. lemnisci lateralis, pars ventrali

LM:

lemniscus medialis

LP:

nucl. lateralis posterior thalami

MD:

nucl. medialis dorsalis thalami

MV:

nucl. motorius n. trigemini

NCS:

nucl. centralis superior

NCT:

nucl. trapezoidalis

NMV:

nucl. mesencephalicus n. trigemini

NR:

nucl. ruber

NSV:

nucl. spinalisn. trigemini

NTS:

nucl. tractus solitarii

NIII:

nucl. oculomotorius

NIV:

nucl. trochlearis

NVI:

nucl. abducens

NVII:

nucl. facialis

NXII:

nucl. hypoglossus

OI:

oliva inferior

OS:

oliva superior

P:

nucl. posterior thalami

PbL:

nucl. parabrachialis lateralis

PbM:

nucl. parabrachialis medialis

PC:

depedunculus cerebri

Pd:

nucl. peripeduncularis

Pg:

nucl. parabigeminalis

Pp:

nucl. praepositus

PuI:

nucl. pulvinaris inferior

PuL:

nucl. pulvinaris lateralis

PuM:

nucl. pulvinaris medialis

PuO:

nucl. pulvinaris oralis

Py:

tractus pyramidalis

Pv:

nucl. principalis n. trigemini

R Ab:

nucl. retroambiguus

RL:

nucl. reticularis lateralis

RTP:

nucl. reticularis tegmenti pontis

Sf:

nucl. subfascicularis

SGD:

substantia grisea dorsalis

SGV:

substantia grisea ventralis

SN:

substantia nigra

ST:

stria terminalis

St:

subthalamus

TRM:

tractus retroflexus (Meynert)

TSc:

tractus spinocerebellaris

Ves:

nucl. vestibularis

VL:

nucl. ventralis lateralis

VPI:

nucl. ventralis posterior inferior

VPL:

nucl. ventralis posterior lateralis

VPM:

nucl. ventralis posterior medialis

VR:

nucl. ventralis raphae

Zi:

zona incerta

II:

tractus opticus

VII:

n. facialis

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Authors and Affiliations

  1. Max-Planck-Institut für Psychiatrie, W-8000, München, Federal Republic of Germany

    Jürgen Dressnandt

  2. Deutsches Primatenzentrum, Kellnerweg 4, W-3400, Göttingen, Federal Republic of Germany

    Uwe Jürgens

Authors
  1. Jürgen Dressnandt
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  2. Uwe Jürgens
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Dressnandt, J., Jürgens, U. Brain stimulation-induced changes of phonation in the squirrel monkey. Exp Brain Res 89, 549–559 (1992). https://doi.org/10.1007/BF00229880

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  • DOI: https://doi.org/10.1007/BF00229880

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