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Myocardial cell lesions caused by an anabolic hormone

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Summary

Early changes in the composition of heart muscle cells of the rat caused by an anabolic hormone were investigated by electron microscopy. Mitochondria and myofibrils showed changes similar to those observed in early heart failure: The mitochondria were swollen and elongated. Their matrix was sparse and the cristae were few in number. The myofibrils showed either disintegration and widened and twisted Z-bands or a complete dissolution of the sarcomeric units.

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Authors and Affiliations

  1. Department of Anatomy, Medical Faculty, Rheinisch-Westfälische Technische Hochschule, Aachen, Federal Republic of Germany

    H. Behrendt & H. Boffin

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  1. H. Behrendt
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  2. H. Boffin
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This work is supported by the Deutsche Forschungsgemeinschaft (Be 742/1)

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Behrendt, H., Boffin, H. Myocardial cell lesions caused by an anabolic hormone. Cell Tissue Res. 181, 423–426 (1977). https://doi.org/10.1007/BF00223116

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  • DOI: https://doi.org/10.1007/BF00223116

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