Summary
ACTH and MSH cells of the pituitary are rich in peptides with NH2-terminal tryptophan, as revealed by fluorescence histochemistry. Adrenalectomy stimulates the ACTH cells but not the MSH cells. As a result, ACTH as well as tryptophyl-peptides disappear from the ACTH cells but not from the MSH cells. It is concluded that the tryptophyl-peptides are stored together with the respective hormone in the ACTH and MSH cells and that tryptophyl-peptides in the ACTH cells are released together with the hormone.
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Håkanson, R., Sundler, F. Formaldehyde-ozone-induced fluorescence in pituitary ACTH cells: Effect of adrenalectomy. Cell Tissue Res. 183, 419–421 (1977). https://doi.org/10.1007/BF00220648
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DOI: https://doi.org/10.1007/BF00220648