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An epidermal proliferative unit-like structure in the epithelium of mouse bladder observed by backscattered electron imaging

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Summary

The simultaneous use of a silver-staining technique, backscattered electron imaging and stereo-tilts has made it possible to visualize the spatial distribution of cell nuclei in the stretched epithelium of the bladder of mice. This study has led to the observation that a structural organization resembling the epidermal proliferative unit, previously found in the skin exists also in bladder epithelium. However, the proliferative unit in the bladder was different in that it contained a higher number of cells per unit, and an absence of columns of inactive squamous cells. These findings may indicate that epidermal proliferative unit-like structures represent a common form of organization in some epithelia.

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Thiébaut, F., Reitan, J.B., Feren, K. et al. An epidermal proliferative unit-like structure in the epithelium of mouse bladder observed by backscattered electron imaging. Cell Tissue Res. 246, 1–6 (1986). https://doi.org/10.1007/BF00218991

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  • DOI: https://doi.org/10.1007/BF00218991

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