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From binding proteins to hormone receptors?

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Abstract

Phytohormones exert in responsive plant cells specific biochemical and physiological effects. It is a widely held view that phytohormones are first recognized by specific receptors which initiate the transduction of the hormonal signal. While hormone receptors are well studied in many eukaryotes ranging from yeast to man, we are lacking a detailed understanding of phytohormone receptors. Phytohormone binding proteins have been suspected to provide candidates for such receptors. In this review recent progress towards molecular analysis of such proteins and their genes will be summarized.

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References

  • Barbier-Brygoo H, Ephritikhine G, Klämbt D, Ghislain M, Guern J (1989) Functional evidence for an auxin receptor at the plasmalemma of tobacco mesophyll protoplasts. Proc Natl Acad Sci USA 86:891–896

    Article  PubMed  CAS  Google Scholar 

  • Barbier-Brygoo H, Ephritikhine G, Klämbt D, Maurel C, Palme K, Schell J, Guern J (1991) Perception of the auxin signal at the plasma membrane of tobacco mesophyll protoplasts. Plant J 1:83–93

    Article  CAS  Google Scholar 

  • Bilang J, Macdonald H, King PJ, Sturm A (1993) A soluble auxin-binding protein from Hyoscamus muticus is a glutathione S-transferase. Plant Physiol 102:29–34

    Article  PubMed  CAS  Google Scholar 

  • Brinegar AC, Stevens A, Fox JE (1985) Biosynthesis and degradation of a wheat embryo cytokinin-binding protein during embryogenesis and germination. Plant Physiol 79:706–710

    PubMed  CAS  Google Scholar 

  • Brinegar AC, Cooper G, Stevens A, Hauer CR, Shabanowitz J, Hunt DF, Fox JE (1985) Characterization of a benzyladenine binding-site isolated from a wheat cytokinin-binding protein: Sequence analysis and identification of a single affinity-labeled histidine residue by mass spectrometry. Proc Natl Acad Sci USA 85:5927–5931

    Article  Google Scholar 

  • Brzobohaty B, Moore I, Kristoffersen P, Bako L, Campos N, Schell J, Palme K (1993) A β-glucosidase that releases active cytokinin is localized in the maize root meristem. Science 262:1051–1054

    Article  PubMed  CAS  Google Scholar 

  • Campos N, Feldwisch J, Zettl R, Boland W, Schell J, Palme K (1991) Identification of auxin binding proteins using an improved assay for photoaffinity labeling with 5-N3-[7-3H]-indole-3-acetic acid. Technique 65:69–75

    Google Scholar 

  • Campos N, Bako L, Feldwisch J, Schell J, Palme K (1992) A protein from maize labeled with azido-IAA has novel β-glucosidase activity. Plant J 2:675–684

    CAS  Google Scholar 

  • Chen C-M, Melitz DK, Petschow B, Eckert RL (1980) Isolation of cytokinin-binding protein from plant tissues by affinity chromatography. Eur J Biochem 108:379–387

    Article  PubMed  CAS  Google Scholar 

  • Davies PJ (1987) Plant hormones and their role in plant growth and development. Martinus Nijhoff Publishers, Dordrecht

    Google Scholar 

  • Dohrmann U, Hertel R, Kowalik W (1978) Properties of auxin binding sites in different subcellular fractions from maize coleoptiles. Planta 140:97–106

    Article  CAS  Google Scholar 

  • Erion JL, Fox JE (1981) Purification and properties of a protein which binds cytokinin-active 67-substituted purines. Plant Physiol 67:156–162

    Article  PubMed  CAS  Google Scholar 

  • Estelle M (1992) The plant hormone auxin: Insight in sight. Bioessays 14:439–444

    Article  PubMed  CAS  Google Scholar 

  • Feldwisch J, Zettl R, Hesse F, Schell J, Palme K (1992) An auxin binding protein is localised to the plasma membrane of maize coleoptile cells: Identification by photoaffinity labeling and purification of a 23 kDa polypeptide. Proc Natl Acad Sci USA 89:475–479

    Article  PubMed  CAS  Google Scholar 

  • Felle H, Peters W, Palme K (1991) The electrical response of maize to auxins. Biochim Biophys Acta 1064:199–204

    Article  PubMed  CAS  Google Scholar 

  • Fox JE, Erion JL (1975) A cytokinin binding protein from higher plant ribosomes. Biochem Biophys Res Commun 64:694–700

    Article  PubMed  CAS  Google Scholar 

  • Hamaguchi N, Iwamura H, Fujita T (1985) Fluorescent anticytokinins as a probe for binding. Isolation of cytokininbinding proteins from the soluble fraction and identification of a cytokinin-binding site on ribosomes of tobacco callus cells. Eur J Biochem 153:565–572

    Article  PubMed  CAS  Google Scholar 

  • Hertel R, Thomson KS, Russo VEA (1972) In vitro auxin binding to particulate cell fractions from corn coleoptiles. Planta 107:325–340

    Article  CAS  Google Scholar 

  • Hesse T, Feldwisch J, Balshüsemann D, Bauw G, Puype M, Vandekerckhove J, Löbler M, Klämbt D, Schell J, Palme K (1989) Molecular cloning and structural analysis of a gene from Zea mays (L.) coding for a putative receptor for the plant hormone auxin. EMBO J 8:2453–2461

    PubMed  CAS  Google Scholar 

  • Hesse T, Garbers C, Brzobohaty B, Kreimer G, Söll D, Melkonian M, Schell J, Palme K (1993) Two members of the ERabp gene family are differentially expressed in reproductive organs from maize but not in the coleoptile. Plant Mol Biol 23:57–66

    Article  PubMed  CAS  Google Scholar 

  • Hicks GR, Rayle DL, Jones AM, Lomax TL (1989a) Specific photoaffinity labeling of two plasma membrane polypeptides with an azido auxin. Proc Natl Acad Sci USA 86:4948–4952

    Article  PubMed  CAS  Google Scholar 

  • Hicks GR, Rayle DL, Lomax TL (1989b) The diageotropica mutant of tomato lacks high specific activity auxin binding sites. Science 245:52–54

    Article  PubMed  CAS  Google Scholar 

  • Hohman RJ, Guitton MC, Veron M (1985) Inactivation of S-adenosyl-L-homocysteine hydrolase by cAMP results from dissociation of enzyme bound-bound NAD+. Proc Natl Acad Sci USA 82:4578–4585

    Article  PubMed  CAS  Google Scholar 

  • Inohara N, Shimomura S, Fukui T, Futai M (1989) Auxinbinding protein located in the endoplasmic reticulum of maize shoots: Molecular cloning and complete structure. Proc Natl Acad Sci USA 86:3564–3568

    Article  PubMed  CAS  Google Scholar 

  • Jacobi A, Zettl R, Palme K, Werner D (1993) An auxin binding protein is localized in the symbiosome membrane of soybean nodules. Z Naturforschung 48c:35–40

    Google Scholar 

  • Jones AM, Melhado LL, Ho T-H, Leonhard NJ (1984) Azido auxins. Quantitative binding data in maize. Plant Physiol 74:295–301

    PubMed  CAS  Google Scholar 

  • Jones AM, Prasad PV (1992) Auxin binding proteins and their possible roles in auxin-mediated plant cell growth. BioEssays 14:43–48

    Article  CAS  Google Scholar 

  • Jones A, Venis MA (1989) Photoaffinity labeling of indole-3 acetic acid-binding proteins from maize. Proc Natl Acad Sci USA 86:6153–6156

    Article  PubMed  CAS  Google Scholar 

  • Jones AM, Herman EM (1993) KDEL-containing auxin-binding protein is secreted to the plasma membrane and cell wall. Plant Physiol 101:595–606

    PubMed  CAS  Google Scholar 

  • Kawallek P, Plesch G, Hahlbrock K, Somssich IE (1992) Induction by fungal elicitor of S-adenosyl-L-methionine synthetase and S-adenosyl-L-homocysteine hydrolase mRNAs in cultured cells and leaves of Petroselinum crispum. Proc Natl Acad Sci USA 89:4713–4717

    Article  Google Scholar 

  • Klee H, Estelle M (1991) Molecular genetic approaches to plant hormone action. Annu Rev Plant Physiol. Plant Mol Biol 42:529–551

    Article  CAS  Google Scholar 

  • Kulaeva ON, Karavaiko NN, Moshkov IE, Selivankina S Yu, Novikova GV (1990) Isolation of a protein with cytokininreceptor properties by means of anti-idiotype antibodies. FEBS Lett 261:410–412

    Article  CAS  Google Scholar 

  • Libbenga KR, Mennes AM (1987) Hormone binding and its role in hormone action. In: Davies PJ (ed) Plant hormones and their role in plant growth and development. Martinus Nijhof Publishers, Dordrecht, pp 194–221

    Google Scholar 

  • Macdonald H, Jones AM, King P (1991) Photoaffmity labeling of soluble auxin-binding proteins. J Biol Chem 266:7393–7399

    PubMed  CAS  Google Scholar 

  • Mitsui S, Sugiura M (1993) Purification and properties of cytokinin-binding proteins from tobacco leaves. Plant Cell Physiol 34:543–547

    CAS  Google Scholar 

  • Momotani E, Tsuji H (1992) Isolation and characterization of a cytokinin-binding protein from the water-soluble fraction of tobacco leaves. Plant Cell Physiol 64:594–599

    Google Scholar 

  • Moore III FH (1979) A cytokinin-binding protein from wheat germ. Isolation by affinity chromatography and properties. Plant Physiol 64:594–599

    PubMed  CAS  Google Scholar 

  • Mornet R, Theiler JB, Leonard NJ, Schmitz RY, Moore III FH, Skoog F (1979) Active cytokinins. Photoaffmity labeling to detect binding. Plant Physiol 64:600–610

    PubMed  CAS  Google Scholar 

  • Napier R, Venis M (1990) Monoclonal antibodies detect an auxin-induced conformational change in the maize auxinbinding protein. Planta 182:313–318

    Article  CAS  Google Scholar 

  • Palme K, Feldwisch J, Hesse T, Bauw G, Puype M, Vandekerckhove J, Schell J (1990) Auxin binding proteins from maize coleoptiles: Purification and molecular properties. In: Roberts JA, Kirk C, Venis M (eds) Hormone perception and signal transduction in animals and plants (vol XLIV). The Company of Biologists Limited, Cambridge, pp 299–313

    Google Scholar 

  • Palme K, Hesse T, Moore I, Campos N, Feldwisch J, Garbers C, Hesse F, Schell J (1991) Hormonal modulation of plant growth: The role of auxin perception. Mech Dev 33:97–106

    Article  PubMed  CAS  Google Scholar 

  • Palme K, Hesse T, Campos N, Garbers C, Yanofsky MF, Schell J (1992) Molecular analysis of an auxin binding protein gene located on chromosome 4 of arabidopsis. Plant Cell 4:193–201

    Article  PubMed  CAS  Google Scholar 

  • Palme K, Schell J (1993) On plant growth regulators and their metabolites: A changing perspective. Sem Cell Biol 4:87–92

    Article  CAS  Google Scholar 

  • Pelham HRB (1990) The retention signal for the soluble proteins of the endoplasmic reticulum. Trends Biochem Sci 15:483–486

    Article  PubMed  Google Scholar 

  • Polya GM, Davis AW (1978) Properties of a high-affinity cytokinin-binding protein from wheat germ. Planta 139:139–147

    Article  CAS  Google Scholar 

  • Poovaiah BW (1982) Strawberry fruit as a model system to study target tissue specificity and the relevance of auxin binding. Plant Physiol 69:5–151

    Google Scholar 

  • Ray PM, Dohrmann U, Hertel R (1977) Specificity of auxinbinding sites on maize coleoptile membranes as possible receptor sites of auxin action. Plant Physiol 60:585–591

    PubMed  CAS  Google Scholar 

  • Romanov GA, Taran V Ya, Venis MA (1990) Cytokinin-binding protein from maize shoots. J Plant Physiol 136:208–212

    CAS  Google Scholar 

  • Rubery PH (1990) Phytotropins: Receptors and endogenous ligands. In: Robert J, Kirk C, Venis M (eds) Hormone perception and signal transduction in animals and plants. Company of Biologists Limited, Cambridge, pp 119–146

    Google Scholar 

  • Rück A, Palme K, Venis MA, Napier R, Felle HH (1993) Patchclamp analysis establishes a role for an auxin binding protein in the auxin stimulation of plasma current in Zea mays protoplasts. Plant J 4:41–46

    Article  Google Scholar 

  • Schwob E, Choi S-Y, Simmons C, Migliaccio F, Ilag L, Hesse T, Palme K, Söll D (1993) Molecular analysis of three maize 22 kDa auxin binding protein genes—transient promoter expression and regulatory regions. Plant J (in press)

  • Shimomura S, Sotobayashi T, Futai M, Fukui T (1986) Purification and properties of an auxin-binding protein from maize shoot membranes. J Biochem 99:1513–1524

    PubMed  CAS  Google Scholar 

  • Shimomura S, Liu W, Inohara N, Watanabe S, Futai M (1993) Structure of the gene for an auxin-binding protein and a gene for 7SL RNA from Arabidopsis thaliana. Plant Cell Physiol 34:633–647

    PubMed  CAS  Google Scholar 

  • Spena A, Estruch JJ, Schell J (1992) On microbes and plants: New insights in phytohormonal research. Curr Opin Biotechn 3:159–163

    Article  CAS  Google Scholar 

  • Stoddart JL, Venis MA (1980) Molecular and subcellular aspects of hormone action. In: MacMillan J (ed) Encyclopedia of plant physiology (vol 9). Springer Verlag, Berlin, pp 445–672

    Google Scholar 

  • Takegami T, Yoshida K (1975) Isolation and purification of cytokinin binding protein from tobacco leaves by affinity column chromatography. Biochem Biophys Res Comm 67:782–789

    Article  PubMed  CAS  Google Scholar 

  • Takegami T, Yoshida K (1977) Specific interactions of cytokininbinding proteins with 40S ribosomal subunits in the presence of cytokinin in vitro. Plant Cell Physiol 18:337–346

    CAS  Google Scholar 

  • Theiler JB, Leonard NJ (1976) Photoaffinity-labeled cytokinins. Plant Physiol 58:803–805

    PubMed  CAS  Google Scholar 

  • Tillmann U, Viola G, Kayser B, Siemeister G, Hesse H, Palme K, Löbler M, Klämbt D (1989) cDNA clones of the auxinbinding protein from corn coleoptiles (Zea mays L.): Isolation and characterization by immunological methods. EMBO J 8:2463–2467

    PubMed  CAS  Google Scholar 

  • Venis MA (1977) Solubilisation and partial purification of auxinbinding sites of corn membranes. Nature 266:268–269

    Article  CAS  Google Scholar 

  • Venis M (1987) Can auxin receptors be purified by affinity chromatography? In: Klämbt D (ed) Plant hormone receptors. (NATO ASI Series H, vol 10). Springer-Verlag, Berlin, pp 27–39

    Google Scholar 

  • Venis MA, Napier RM, Barbier-Brygoo H, Maurel C, Perrot-Rechenmann C, Guern J (1992) Antibodies to a peptide from the maize auxin-binding protein have auxin agonist activity. Proc Natl Acad Sci USA 89:7208–7212

    Article  PubMed  CAS  Google Scholar 

  • Walton DJ, Ray PM (1981) Evidence for receptor functions of auxin binding sites in maize. Red light inhibition of mesocotyl elongation and auxin binding. Plant Physiol 68:1334–1338

    PubMed  CAS  Google Scholar 

  • Yu L-X, Lazarus CM (1991) Structure and sequence of an auxinbinding protein gene from maize (Zea mays L.). Plant Mol Biol 16:925–930

    Article  PubMed  CAS  Google Scholar 

  • Zettl R, Campos N, Boland W, Schell J, Palme K (1991) 5′Azido-[3,6-3H2]-naphthylphtalamic acid, a photoactivatable probe for auxin efflux carrier proteins. Technique 3:151–158

    Google Scholar 

  • Zettl R, Feldwisch J, Boland W, Schell J, Palme K (1992) Azido[3,6-3H2]-N-1-naphthylphtalamic acid, a novel photoactivatable probe for auxin efflux carrier proteins from higher plants: Identification of a 23 kDa protein from maize coleoptile plasma membranes. Proc Natl Acad Sci USA 89:480–4884

    Article  PubMed  CAS  Google Scholar 

  • Zettl R, Schell J, Palme K (1994) Photoaffinity labeling of Arabidopsis thaliana plasma membranes by 5-azido-[7-3H]-indole-3-acetic acid: Identification of a glutathione S-transferase. Proc Natl Acad Sci USA (in press)

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  1. Max-Planck-Institut für Züchtungsforschung, D-50829, Köln, Germany

    Klaus Palme

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  1. Klaus Palme
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Palme, K. From binding proteins to hormone receptors?. J Plant Growth Regul 12, 171–178 (1993). https://doi.org/10.1007/BF00213035

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