Summary
We describe a simple method for characterizing a frequent polymorphism (that subsitutes an arginine for a proline) in the coding sequence of the Tp53 gene in patients with colonic cancer and in a control population. We could find no evidence that this polymorphism is associated with a marked predisposition to colorectal cancer.
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Olschwang, S., Laurent-Puig, P., Vassal, A. et al. Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population. Hum Genet 86, 369–370 (1991). https://doi.org/10.1007/BF00201836
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DOI: https://doi.org/10.1007/BF00201836