References
Astroff B, Safe S (1988) Comparative antiestrogenic activities of 2,3,7,8-TCDD and 6-methyl-1,3,8-trichloro-dibenzofuran in the female rat. Toxicol Appl Pharmacol 95:435–443.
Bitman J, Cecil HC (1970) Estrogenic activity of DDT analogs and polychlorinated biphenyls. J Agr Food Chem 1:1108–1112.
Brouwer A (1989) Inhibition of thyroid hormone transport in plasma of rats by polychlorinated biphenyls. Arch Toxicol Suppl 13: 440–445.
Ecobichon DJ, Mackenzie DO (1974) The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rats. Res Commun Chem Pathol Pharmacol 9:85–94.
Hansen LG (1979) Selective accumulation and depletion of polychlorinated biphenyl components: food animal implications. Ann NY Acad Sci 320:238–246.
Hansen LG (1987) Food chain modification of the composition and toxicity of polychlorinated biphenyl residues. Rev Environ Toxicol 3:149–212.
Jansen HT, Cooke PS, Porcelli J, Liu T-C, Hansen LG (1993) Estrogenic and antiestrogenic actions of PCBs in the female rat: In vitro and In vivo studies. Reprod Toxicol 7:237–248.
Kaminsky LS, Kennedy MW, Adams SM, Guengerich FP (1981) Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome P450. J Biochem 20:7379–7384.
Korach KS, Sarver P, Chae K, McLachlan JA, Mckinney JD (1988) Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: Conformationally restricted structural probes. Mol Pharmacol 33:120–126.
Krishnan V, Safe S (1993) Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: Quantitative structure-activity relationships. Toxicol Appl Pharmacol 120:55–61.
Kupfer D, Bulger WH (1982) Estrogenic actions of chlorinated hydrocarbons. In Effects of Chronic Exposures to Pesticides on Animal Systems. (JE Chambers, JD Yarbrough, Eds.), pp. 121–146. Raven Press, New York.
Lowery OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275.
Morse DC, Koeter HBWM, Smits van Prooijen AE, Brouwer A (1992) Interference of polychlorinated biphenyls in thyroid hormone metabolism: Possible neurotoxic consequences in fetal and neonatal rats. Chemosphere 25:165–168.
Ness DK, Schantz SL, Moshtaghian J, Hansen LG (1993) Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat. Toxicol Lett 68:311–323.
Pohl RA, Fouts RJ (1980) A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Anal Biochem 107:150–155.
Sipes IG, Schnellmann RG (1987) Biotransformation of PCBs: Metabolic pathways and mechanisms. Environ Toxin Ser 1:97–110.
Wolff MS, Toniolo PG, Lee EW, Rivera M, Dubin N (1993) Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst 85:648–652.
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Li, M.H., Zhao, Y.D. & Hansen, L.G. Multiple dose toxicokinetic influence on the estrogenicity of 2,2′,4,4′,5,5′-hexachlorobiphenyl. Bull. Environ. Contam. Toxicol. 53, 583–590 (1994). https://doi.org/10.1007/BF00199030
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DOI: https://doi.org/10.1007/BF00199030