Abstract
The typical giant cell tumor (GCT) is a solitary neoplasm that occurs in the epiphysis or epimetaphysis of long bones. GCT is seen with a slightly increased frequency in females, and 70% of patients are between 20 and 40 years of age at the time of presentation. Multicentric giant cell tumor (MGCT; two or more centers) is an unusual variant of GCT. Patients with MGCT are likely to be younger than those with a solitary lesion. The multicentric variety is often of a higher stage at diagnosis and is more often associated with a pathological fracture than the unifocal tumor. We are reporting five new cases of MGCT, with a total of 21 tumors seen over a period of 25 years from 1967 to 1992.
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Hindman, B.W., Seeger, L.L., Stanley, P. et al. Multicentric giant cell tumor: report of five new cases. Skeletal Radiol. 23, 187–190 (1994). https://doi.org/10.1007/BF00197457
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DOI: https://doi.org/10.1007/BF00197457