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Laparoscopic intra-arterial catheter implantation for regional chemotherapy of liver metastasis

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Abstract

In patients with unresectable metastatic disease confined to the liver, intra-arterial regional chemotherapy with implantable systems is an attractive option. Since April 1992, laparoscopic colorectal resections have been performed in our institution. Within this series of patients, three cases with bilateral liver metastasis from colon cancer were observed and underwent laparoscopic intra-arterial catheter implantation in the gastroduodenal artery for regional chemotherapy. In two patients the metastases were synchronous, and in both cases a laparoscopic colon resection was also performed, for tumors located in the cecum and in the sigmoid colon, respectively. The laparoscopic surgical technique for intra-arterial catheter implantation is described in detail. In this limited experience the procedure, from a purely technical point of view, was not considered difficult and was completed in 70 min on average. No complications were observed and the patient with metachronous liver metastasis was discharged on 3rd postoperative day.

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References

  1. Blackshear RJ, Rhode TD, Varco RL, Bucwald H (1975) One year of continuous heparinization in the day using a totally implantable infusion pump. Surg Gynecol Obstet 141: 176–186

    Google Scholar 

  2. Curley SA, Hohn DC, Roh MS (1990) Hepatic artery infusion pumps: cannulation techniques and other surgical considerations. Langenbecks Arch Chir 375: 119–124

    Google Scholar 

  3. Curley SA, Chase JL, Roh MS, Hohn DC (1993) Technical considerations and complications associated with the placement of 180 implantable hepatic arterial infusion devices. Surgery 114: 928–935

    Google Scholar 

  4. Curley SA, Roh MS, Chase JL (1993) Adjuvant hepatic arterial infusion chemotherapy after curative resection of colorectal liver metastases. Am J Surg 166: 743–748

    Google Scholar 

  5. De Takats PG, Kerr DJ, Poole CJ, Warren HW, McArdle CS (1994) Hepatic arterial chemotherapy for metastatic colorectal carcinoma. Br J Cancer 69: 372–378

    Google Scholar 

  6. Ensminger W, Niederhuber J, Dakhil S, Thral J, Wheeler R (1981) Totally implanted drug delivery system for hepatic arterial chemotherapy. Cancer Treat 65: 393–400

    Google Scholar 

  7. Foster JW (1978) Survival after liver resection for secondary tumor. Am J Surg 135: 389–384

    Google Scholar 

  8. Friedman M (1979) Combined modality therapy of hepatic metastasis. Cancer 44: 906–913

    Google Scholar 

  9. Gennari L, Quagliolo V, Bignami P (1992) La chemioterapia locoregionale nelle neoplasie. Minerva Chir 47: 1079–1090

    Google Scholar 

  10. Horgan PG, Fitzpatrik M, Couse NF, Gorey TF, Fitzpatrik JM (1992) Laparoscopy is less immunotraumatic than laparotomy. Minimally Inv Ther 1: 241–244

    Google Scholar 

  11. Kane RA (1993) Ultrasound-guided hepatic cryosurgery for tumor ablation. Semin Interv Radiol 10(2): 132–144

    Google Scholar 

  12. Lien WM, Ackerman NB (1970) The blood supply of experimental liver metastases II. A microcirculatory study of the normal and tumor vessels of the lever with the use of perfused silicone rubber. Surgery 68: 334–340

    Google Scholar 

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Feliciotti, F., Paganini, A., Guerrieri, M. et al. Laparoscopic intra-arterial catheter implantation for regional chemotherapy of liver metastasis. Surg Endosc 10, 449–452 (1996). https://doi.org/10.1007/BF00191639

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  • DOI: https://doi.org/10.1007/BF00191639

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