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Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11

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References

  • Bosma, G. C., Custer, R. P., and Bosma, M. J.: A severe combined immunodeficiency mutation in the mouse. Nature 301: 527–530, 1983

    Google Scholar 

  • Bosma, G. C., Davisson, M. T., Ruetsch, N. R., Sweet, H. O., Shultz, L. D., and Bosma, M. J.: The mouse severe combined immune deficiency (scid) is on chromosome 16. Immunogenetics 29: 54–57, 1989

    Google Scholar 

  • Bruhn, S. L., Pil, P. M., Essigmann, J. M., Housman, D. E., and Lippard, S. J.: Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin. Proc Natl Acad Sci USA 89: 2307–2311, 1992

    Google Scholar 

  • Early, P., Huang, H., Davis, M. M., Calame, K., and Hood, L.: An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D, and JH. Cell 19: 981–992, 1980

    Google Scholar 

  • Goebl, M. G., Moreau-Gachelin, F., Ray, D., Tambourin, A., Tavitian, A., Klemsz, M. J., McKercher, S. R., Celada, A., van Beveren, C., and Maki, R. A.: The PU.1 transcription factor is the product of the putative oncogene Spi-1. Cell 61: 1165–116, 1990

    Google Scholar 

  • Goff, S., Gilboa, E., Witte, O., and Baltimore, D.: Structure of the Abelson genome and the homologous cellular gene: studies with cloned viral DNA. Cell 22: 777–785, 1980

    Google Scholar 

  • Hermanson, G. G., Lichter, P., Selleri, L., Ward, D. C., and Evans, G. A.: Cosmid linking clones localized to the long arm of human chromosome 11. Genomics 13: 134–143, 1992

    Google Scholar 

  • Hori, T.-A., Takahashi, E.-I., Tanigami, A., Tokino, T., and Nakamura, Y.: A high resolution cytogenetic map of 168 cosmid DNA markers for human chromosome 11. Genomics 13: 129–133, 1992

    Google Scholar 

  • Klemsz, M. J., McKercher, S. R., Celada, A., van Beveren, C., and Maki, R. A.: The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene. Cell 61: 113–124, 1990

    Google Scholar 

  • Klemsz, M. J., McKercher, S. R., and Maki, R. A.: Nucleotide sequence of the mouse hck gene. Nucleic Acids Res 15: 9600, 1987

    Google Scholar 

  • Kronenberg, M., Siu, G., and Hood, L.: The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. Annu Rev of Immunol 4: 529–591, 1986

    Google Scholar 

  • Max, E. E., Seidman, J. G., and Leder, P.: Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene. Proc Natl Acad Sci USA 76: 3450–3454, 1979

    Google Scholar 

  • Oakey, R. J., Howard, T. A., Hogarth, P. M., Tani, K., and Seldin, M. F.: Chromosomal mapping of the high affinity Fcγ receptor gene. Immunogenetics 35: 279–282, 1992

    Google Scholar 

  • Oettinger, M. A., Schatz, D. G., Gorka, C., and Baltimore, D.: RAG-1 and RAG-2: adjacent genes that synergistically activate V(D)J recombination. Science 248: 1517–1523, 1990

    Google Scholar 

  • Oettinger, M. A., Stanger, B., Schatz, D. G., Glaser, T., Call, K., Housman, D., and Baltimore, D.: The recombination activating genes, RAG 1 and RAG 2, are on chromosome 11p in humans and chromosome 2p in mice. Immunogenetics 35: 97–101, 1992

    Google Scholar 

  • Sakano, H., Huppi, K., Heinrich, G., and Tonegawa, S.: Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature 280: 288–294, 1979

    Google Scholar 

  • Schatz, D. G., Oettinger, M. A., and Baltimore, D.: The V(D)J recombination activating gene (RAG-1). Cell 59: 1035–1048, 1989

    Google Scholar 

  • Shirakata, M., Huppi, K., Usuda, S., Okazaki, K., Yoshida, K., and Sakano, H.: HMG1-related DNA-bindding protein isolated with V(D)J recombination signal probes. Mol Cell Biol 11: 4528–4536, 1991

    Google Scholar 

  • Siracusa, L. and Abbott, C. M.: Mouse chromosome 2. Mamm Gen 1: S18-S41, 1991

    Google Scholar 

  • Tonegawa, S.: Somatic Generation of antibody diversity. Nature 302: 575–581, 1983

    CAS  PubMed  Google Scholar 

  • Van Cong, N., Ray, D., Gross, M. S., de Tand, M. F., Frezal, J., and Moreau-Gachelin, F.: Localization of the human oncogene SPI1 on chromosome 11, region p11.22. Hum Genet 84: 542–546, 1990

    Google Scholar 

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Huppi, K., Siwarski, D., Shaughnessy, J. et al. Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11. Immunogenetics 37, 288–291 (1993). https://doi.org/10.1007/BF00187456

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  • DOI: https://doi.org/10.1007/BF00187456

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