Abstract
• Background: We wanted to evaluate whether intracameral injection of tissue plasminogen activator (tPA) is useful in managing traumatic hyphaema.
• Methods: Two eyes with total hyphaema after a severe penetrating injury were treated with a single intracameral injection of 25 μg of tPA 5 and 14 days after the injury, respectively.
• Results: Most of the blood coagulum dissolved within 24 h, and in one of the two eyes the intraocular pressure decreased from 45 to 8 mmHg. The other eye was hypotonic. No re-bleeding or complications related to the use of tPA were noticed.
• Conclusion: The results in these two cases suggest that tPA is a useful adjunct in managing total hyphaema.
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Laatikainen, L., Mattila, J. The use of tissue plasminogen activator in post-traumatic total hyphaema. Graefe's Arch Clin Exp Ophthalmol 234, 67–68 (1996). https://doi.org/10.1007/BF00186522
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DOI: https://doi.org/10.1007/BF00186522