Summary
The development of the rat organ of Corti was studied during the first postnatal weeks. The temporal and the spatial patterns of cochlear development were investigated between 4 and 24 days after birth by means of semi-thin sections at approx. ten equidistant positions along the entire cochlear duct. At all examined positions width, thickness and cross sectional area of basilar membrane, cross-sectional area of tectorial membrane, of cells of Hensen, Claudius and Boettcher and of the organ of Corti were quantitatively analyzed. The most conspicuous maturational changes occur between 8 and 12 days after birth. These are the detachment of the tectorial membrane, the first appearance of filaments within the basilar membrane, the formation of the tunnel of Corti and the opening of the inner spiral sulcus. Quantitative analysis revealed that structures of a given position along the cochlear duct do not develop synchronously. Width of the basilar membrane and cross-sectional area of the tectorial membrane are already mature at the onset of hearing (10–12 days after birth). Length, thickness and cross-sectional area of the basilar membrane as well as cross-sectional area of the organ of Corti and of the cells of Hensen, Claudius and Boettcher still develop after the onset of hearing (up to 20–24 days after birth). We suggest that basic cochlear function is established by structures which are mature before the onset of hearing. Cochlear structures which develop after the onset of hearing might be involved in this improvement during this period.
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References
Ballast L (1984) Funktionelle Morphologie der Cochlea von Wildformen und Laborstämmen der Muridae (Rodentia). Dissertation, JW Goethe University Frankfurt/M, FRG
Bruns V, Anton S, Wied C, Gottschalk B, Plassmann W (1985) Postnatal development of the Corti-organ in gerbils. Soc Neurosci 11:245
Burda H, Ballast L, Bruns V (1988) Cochlea in old world mice and rats (Muridae). J Morphol 198:269–285
Crowley D, Hepp-Reymond M (1966) Development of cochlear function in the ear of the infant rat. J Comp Physiol Psychol 62:427–432
Dannhof BJ, Bruns V (1991) The organ of Corti in the bat Hipposideros bicolor. Hear Res 53:253–268
Harris DM, Rotche R, Freedom T (1990) Postnatal growth of cochlear spiral in mongolian gerbil. Hear Res 50:1–6
Henson MM, Jenkins DB, Henson OW Jr (1983) Sustentacular cells of the organ of Corti-the tectal cells of the outer tunnel. Hear Res 10:153–166
Iurato S (1961) Submicroscopic structure of the membranous labyrinth. 2. The epithelium of Corti's organ. Z Zellforsch Mikrosk Anat 53:259–298
Iurato S (1962) Submicroscopic structure of the membranous labyrinth. 3. The supporting structures of Corti's organ (basilar membrane, limbus spiralis and spiral ligament). Z Zellforsch Mikrosk Anat 56:40–96
Kraus HJ, Aulbach-Kraus K (1981) Morphological changes in the cochlea of the mouse after the onset of hearing. Hear Res 4:89–102
Kronester-Frei A (1979) The effect of changes in endolymphatic ion concentrations on the tectorial membrane. Hear Res 1: 81–94
Lavigne-Rebillard M, Pujol R (1987) Surface aspects of the developing human organ of Corti. Acta Otolaryngol [Suppl] 436:43–50
Lenoir M, Shnerson A, Pujol R (1980) Cochlear receptor development in the rat with emphasis on synaptogenesis. Anat Embryol 160:253–262
Lenoir M, Puel JL, Pujol R (1987) Stereocilia and tectorial membrane development in the rat cochlea. A SEM study. Anat Embryol 175:477–487
Lim D (1980) Cochlear anatomy related to cochlear micromechanics. A review. J Acoust Soc Am 67:1686–1695
Lim D (1987) Development of the tectorial membrane. Hear Res 28:9–21
Müller M (1991) Developmental changes of frequency representation in the rat cochlea. Hear Res 56:1–7
Puel JL, Uziel A (1987) Correlative development of cochlear action potential sensitivity, latency and frequency selectivity. Dev Brain Res 37:179–188
Pujol R, Hilding D (1973) Anatomy and physiology of the onset of auditory function. Acta Otolaryngol 76:1–10
Pujol R, Marty R (1970) Postnatal maturation in the cochlea of the cat. J Comp Neurol 139:115–126
Pujol R, Carlier E, Devigne C (1978) Different patterns of cochlear innervation during the development of the kitten. J Comp Neurol 177:529–536
Retzius L (1884) Das Gehörorgan der Wirbeltiere. II. Das Gehörorgan der Reptilien, der Vögel und der Säugetiere. In: Samson, Wallin (eds) Stockholm, pp 313–327
Roth B (1990) Postnatale Entwicklung des Cortischen Organs von Rattus norvegiens. Dissertation, JW Goethe University Frank-furt/M, FRG
Rubel E (1978) Ontogeny of structure and function in the vertebrate auditory system. In: Jacobson M (ed) Handbook of sensory physiology IX, Development of sensory systems. Springer, New York, pp 135–237
Spoendlin H, Brun JP (1974) The block-surface technique for evaluation of cochlear pathology. Arch Oto-Rhino-Laryngol 208:137–145
Thorn L (1975) Die Entwicklung des Cortischen Organs beim Meerschweinchen. Adv Anat Embryol 51:1–97
Uziel A, Romand R, Marot M (1981) Development of cochlear potentials in rats. Audiol 20:89–100
Wada T (1923) Anatomical and physiological studies on the growth of the inner ear of the albino rat. Am Anat Mem 10:1–174
Walther Y, Wess FP, Müller M, Bruns V (1990) The peripheral auditory system in the juvenile and adult grey short-tailed opossum (Monodelphis domestica). In: Elsner N, Roth G (eds) Brain-Perception-Cognition. Proc 18th Neurobiol Conf, p 157
Yancey L, Dallos P (1985) Ontogenetic changes in cochlear characteristic frequency at a basal turn location as reflected in the summating potential. Hear Res 18:189–195
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Roth, B., Bruns, V. Postnatal development of the rat organ of Corti. Anat Embryol 185, 559–569 (1992). https://doi.org/10.1007/BF00185615
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DOI: https://doi.org/10.1007/BF00185615