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Hemi-naevus of Ota : perturbation of neural crest differentiation as a likely mechanism

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Abstract

We present a case of oculodermal melanosis that involves the lower eyelid and lower half of the globe in a very clearly defined fashion. We suggest that such a lesion is the result of a local change in embryonic environment occurring during a well-defined stage of ocular development, such that differentiation of neural crest cells into a melanocytic phenotype is favoured.

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  1. Department of Ophthalmology, Royal Hallamshire Hospital, S10 2JF, Sheffield, UK

    Mark T. Benson & Ian G. Rennie

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  1. Mark T. Benson
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Benson, M.T., Rennie, I.G. Hemi-naevus of Ota : perturbation of neural crest differentiation as a likely mechanism. Graefe's Arch Clin Exp Ophthalmol 230, 226–229 (1992). https://doi.org/10.1007/BF00176293

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  • DOI: https://doi.org/10.1007/BF00176293

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