Abstract
Eye-movement recordings may be helpful in the differentiation of Duane's syndrome from sixth-cranial-nerve palsy. Voluntary horizontal saccades were recorded and quantitated by electrooculography in 18 patients with unilateral type I Duane's syndrome and in 25 patients with sixth-nerve palsy. When ranges of abduction were matched, the peak velocities of abducting saccades in affected eyes were decreased equally in both groups. However, the peak velocities of adducting saccades in sound eyes were slowed in patients with Duane's syndrome. Because the standard deviations in saccadic velocities are large, computer-based, stepwise discriminant analyses were performed to identify the variables that proved to be useful in differentiating the two disorders. By entering these variables into the discriminant functions that were created, we could distinguish Duane's syndrome from sixth-nerve palsy in a statistically significant manner.
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This research was supported in part by a Manpower Award from Research to Prevent Blindness, Inc. (J.B.B.), the Dolly Green Research Scholar Award, RPB Inc. (R.D.Y.), and NEI grant EY068772 (J.B.B.)
Offprint requests to: J. Bronwyn Bateman
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Yang, M.C., Bateman, J.B., Yee, R.D. et al. Electrooculography and discriminant analysis in Duane's syndrome and sixth-cranial-nerve palsy. Graefe's Arch Clin Exp Ophthalmol 229, 52–56 (1991). https://doi.org/10.1007/BF00172261
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DOI: https://doi.org/10.1007/BF00172261