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Systemic autonomic neuropathy in open-angle glaucoma

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Abstract

Systemic autonomic nerve function was assessed in 67 patients with open-angle glaucoma and 76 age- and sex-matched control subjects, using a series of well-established tests based upon cardiovascular reflex responses to standardised stimuli. Parasympathetic neuropathy was present in 37.3% of open-angle glaucoma patients compared with 2.6% of the control group. Demonstration of a significant association between autonomic neuropathy and primary glaucoma may provide a logical rationale for the efficacy of autonomic medication in glaucoma therapeutics; the prognostic implications are discussed.

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Authors and Affiliations

  1. Glaucoma Unit, St Paul's Eye Hospital, Old Hall Street, L3 9PF, Liverpool, UK

    Charles V. Clark & Roy Mapstone

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  1. Charles V. Clark
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  2. Roy Mapstone
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Clark, C.V., Mapstone, R. Systemic autonomic neuropathy in open-angle glaucoma. Doc Ophthalmol 64, 179–185 (1987). https://doi.org/10.1007/BF00159992

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  • DOI: https://doi.org/10.1007/BF00159992

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