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Irrigation with mercury chloride and sodium hypochlorite to prevent local recurrence after excision of conjunctival melanoma An experimental study

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Abstract

Two chemical agents, sodium hypochlorite 0.5% (Dakin's solution) and mercury chloride 0.1%, capable of killing seeded tumour cells, were used for washing the cornea and conjunctiva of rabbits. Both agents produced considerable superficial lesions in the cornea and conjunctiva after irrigation for 3 and 5 min, but these were restored to normal after 2 weeks.

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References

  • Collier RG, Ey RC, McDonald GO and Cole WM (1959) Wound irrigation to prevent local recurrence of cancer. Arch Surg 78:528–534

    Google Scholar 

  • Crawford JB (1980) Conjunctival melanomas: prognostic factors. A review and an analysis of a series. Trans Amer Ophthal Soc 78:467–502

    Google Scholar 

  • Jay B (1965) Naevi and melanomata of the conjunctiva. Brit J Ophthal 49:169–204

    Google Scholar 

  • Liesegang TJ and Campbell RJ (1980) Mayo clinic experience with conjunctival melanomas. Arch Ophthal 98:1385–1389

    Google Scholar 

  • Lopes Cardozo P, Oosterhuis JA, Wolff-Rouendaal D de (1981) Exfoliative cytology in the diagnosis of conjunctival tumours. Ophthalmologica 182:157–164

    Google Scholar 

  • McDonald GO, Gines SM and Cole WH (1960) Wound irrigation in cancer surgery. Arch Surg 60:920–927

    Google Scholar 

  • Oates GD, Mehigan JT and Hoppe ET (1965) Experimental irrigation of subcutaneous wounds and peritoneal cavity with Milton hypochlorite solution after inoculation with cancer cells. Lancet 1:1241–1243

    Google Scholar 

  • Oosterhuis JA and Wolff-Rouendaal D de (1983) Local metastasis in conjunctival melanoma. Docum Ophthal 56:55–59

    Google Scholar 

  • Smith RR (1964) The biological approach to cancer surgery. Postgrad Med 35:395–401

    Google Scholar 

  • Wolff-Rouendaal D de and Oosterhuis JA (1983) Conjunctival melanomas in the Netherlands: a follow-up study. Docum Ophthal 56:49–54

    Google Scholar 

  • Zwaveling A and Vroom EM (1966) Topical use of cancerocidal agents in an experimental model. Arch Chir Neerl 18:273–282

    Google Scholar 

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Authors and Affiliations

  1. Department of Ophthalmology, Leiden University Medical Centre, Leiden, The Netherlands

    J. L. Van Delft, D. De Wolff-Rouendaal & J. A. Oosterhuis

Authors
  1. J. L. Van Delft
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  2. D. De Wolff-Rouendaal
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  3. J. A. Oosterhuis
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Van Delft, J.L., De Wolff-Rouendaal, D. & Oosterhuis, J.A. Irrigation with mercury chloride and sodium hypochlorite to prevent local recurrence after excision of conjunctival melanoma An experimental study. Doc Ophthalmol 56, 61–67 (1983). https://doi.org/10.1007/BF00154710

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  • DOI: https://doi.org/10.1007/BF00154710

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