Abstract
The effects of regular daily coffee consumption on liver enzymes were studied in a large number of subjects from the general population. In coffee drinkers, liver enzymes (gamma-glutamyl transferase, alkaine-amino transferase, and alkaline phosphatase) and serum bilirubin were lower than in non-coffee-drinking subjects or in those consuming less than 3 cups daily. The hypothesis proposed is that liver enzymes are a target for caffeine contained in coffee.
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CasigliaE., MorminoP., SpolaoreP., CernettiC., CostaF. and AmbrosioG.B. (1990): Cardiovascular effects of coffee consumption in the elderly: the CASTEL study - Cardiologia 35: 827–832.
CasigliaE., SpolaoreP., MorminoP., Maschio0., ColangeliG., CelegonL., MaggioloG., TittotoL., PasinatoA. and AmbrosioG.B. (1991): The CASTEL project (Cardiovascular Study in Elderly: protocol, study design, and preliminary results of the initial survey - Cardiologia 36: 569–576.
CasigliaE., PaleariC.D., PetuccoS., BongioviS., ColangeliG., BaccillieriM.S., PavanL. and PessinaA.C. (1992): Haemodynamic effects of coffee and purified caffeine in normal volunteers: a placebo-controlled clinical study - J. Human Hypertension 6: 95–99.
CuratoloP.W. and RobertsonD. (1983): The health consequences of caffeine - Ann. Intern. Med. 98: 641–653.
DuBoisD. and DuBoisF. (1916): A formula to estimate the approximative surface area if height and weight are known - Arch. Int. Med. 17: 863–871.
TeicholzL.E., KreulenT., HermanM.Y. and GorlinR. (1976): Problems in echocardiographic volume determinations: echocardiographic and angiographic correlations in the presence or absence of asynergy - Am. J. Cardiol. 37: 7–11.
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Casiglia, E., Spolaore, P., Inocchio, G. et al. Unexpected effects of coffee consumption on liver enzymes. Eur J Epidemiol 9, 293–297 (1993). https://doi.org/10.1007/BF00146266
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DOI: https://doi.org/10.1007/BF00146266