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Acyclovir treatment in stromal herpetic keratitis

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Abstract

Twenty-five patients with long standing deep stromal herpetic keratitis and iritis were treated with acyclovir (3%) ointment and corticosteroids. All patients healed in about two to four weeks, independent of the duration of the keratitis before acyclovir treatment and independent of the antiviral medication given previously. Recurrences could not be prevented by acyclovir treatment. No serious side effects of acyclovir were noted.

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References

  • Denis-Lassalle J (1970) Uvéites virales. In: Campinchi R, Faure JP, Bloch-Michel E and Haut J: L'Uvéite. Phénomènes immunologiques et allergiques. Masson, Paris, p 615–682

    Google Scholar 

  • Kaufman HE, Martola EL and Dohlman CH (1963) Herpes simplex treatment with IDU and corticosteroids. Trans Amer Acad Ophthal Otolaryng 67:695–701

    Google Scholar 

  • La Lau C, Oosterhuis JA, Versteeg J, van Rij G, Renardel de Lavalette JGC, Craandijk A, Lamers WRMJ and Mierlobensteyn Th (1981) Acyclovir and Trifluorothymidine in herpetic keratitis. Preliminary report of a multicentered trial. Docum Ophthal 50:287–290

    Google Scholar 

  • La Lau C, Oosterhuis JA, Versteeg J, van Rij G, Renardel de Lavalette JGC, Craandijk A and Lamers WPMA (1982) Acyclovir and trifluorothymidine in herpetic keratitis: a multicentred trial. Brit J Ophthal 66:506–508

    Google Scholar 

  • Oosterhuis JA, Versteeg J, Kruit PJ and Postma BH (1980) Acyclovir treatment in experimental herpetic keratitis in rabbits. Ophthal Res 12:38–44

    Google Scholar 

  • Pavan-Langston D, Lass J, Hettinger M and Udell I (1981) Acyclovir and vidarabine in the treatment of ulcerative herpes simplex keratitis. Amer J Ophthal 92:829–835

    Google Scholar 

  • Poirier RH (1982) Aqueous penetration characteristics of three antiviral compounds, TFT, Ara-AMP and Acycloguanosine. Amer J Med Suppl '82 (in press)

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Authors and Affiliations

  1. Departments of Ophthalmology and Virology, Leiden University Medical Centre, Leiden, The Netherlands

    R. Van Ganswijk, J. A. Oosterhuis, M. Swart-Van Den Berg & J. Versteeg

Authors
  1. R. Van Ganswijk
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  2. J. A. Oosterhuis
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  3. M. Swart-Van Den Berg
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  4. J. Versteeg
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Van Ganswijk, R., Oosterhuis, J.A., Den Berg, M.SV. et al. Acyclovir treatment in stromal herpetic keratitis. Doc Ophthalmol 55, 57–61 (1983). https://doi.org/10.1007/BF00140462

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  • DOI: https://doi.org/10.1007/BF00140462

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