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Continuous production of phenylalanine using an Escherichia coli regulatory mutant

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Summary

Phenylalanine synthesis from glucose and ammonia was studied using a hyperproducing mutant of Escherichia coli. Kinetic parameters (typical values : 8.7 g phenylalanine/l, yield on glucose 0.19 g/g, productivity 0.44 g/l/h) were similar to batch culture values.

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Choi, Y.J., Tribe, D.E. Continuous production of phenylalanine using an Escherichia coli regulatory mutant . Biotechnol Lett 4, 223–228 (1982). https://doi.org/10.1007/BF00132390

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  • DOI: https://doi.org/10.1007/BF00132390

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