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Citric acid production by Yarrowia lipolytica: Effect of nitrogen and biomass concentration on yield and productivity

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Summary

Citric acid yields of Yarrowia lipolytica (NRRL Y-1095) grown on glucose ranged from 0.38–0.77 g/g and were dependent on both biomass and nitrogen concentration (as NH4Cl and yeast extract). Increasing the biomass concentration by 3% (w/v) increased fermentor productivities from 0.6 to 1.22 g citric acid/L h.

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References

  • Abou-Zeid, A.Z.A. and Mohamed A.A. (1984). Agricultural Wastes, 9, 51–76.

    Google Scholar 

  • Bailey, J.E. and Ollis, D.F. (1986). Kinetics of substrate utilization, product formation, and biomass production in cell cultures. In Biochemical Engineering Fundamentals, pp. 373–454, McGraw-Hill Book Company, NY.

    Google Scholar 

  • Briffaud, J. and Engasser, M. (1979). Biotechnol. Bioeng., 21, 2083–2092.

    Google Scholar 

  • Enzminger, J.D. and Asenjo, J.A. (1986). Biotechnol. Lett., 8(1), 7–12.

    Google Scholar 

  • Gaden, E. L. (1959). J. Biochem. Microbiol. Tech. Eng., 1, 413–429.

    Google Scholar 

  • Good, D.W., Droniuk, R., Lawford, R. G. and Fein J. E. (1985). Can. J. Microbiol., 31, 436–440.

    Google Scholar 

  • Kim, E.K., Ambriano, J.R. and Roberts, R.S. (1987). Biotechnol. Bioeng., 30(6), 805–808.

    Google Scholar 

  • Klasson, T.K., Clausen, and Gaddy, J.L. (1989). Appl. Biochem. Biotechnol., 20/21, 491–509.

    Google Scholar 

  • Mandeva, R.D., Ermakova, I.T., and Lozinov, A.B. (1981). Mikrobiologiya, 50(1), 62–68.

    Google Scholar 

  • Potvin, J., Desrochers, M. and Arcand, Y. (1988). Appl. Microbiol. Biotechnol., 28(4/5), 350–355.

    Google Scholar 

  • Rane, K.D. and Sims, K.A. (1993). Enzyme Microb. Technol., 15, 646–651.

    Google Scholar 

  • Rane, K.D. and Sims, K.A. (1994). Biotechnol. Bioeng., 43, 131–137.

    Google Scholar 

Download references

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Author notes

  1. Kishore D. Rane

    Present address: Agricultural Bioprocess Lab., University of Illinois, 1302 W. Pennsylvania Av., 61801, Urbana, IL, USA

  2. Kevin A. Sims

    Present address: Mead Johnson Research Center, 47721-0001, Evansville, IN, USA

Authors and Affiliations

  1. Department of Food Science and Technology, Food Science Building, The University of Georgia, 30602-7610, Athens, GA, USA

    Kishore D. Rane & Kevin A. Sims

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  1. Kishore D. Rane
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  2. Kevin A. Sims
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Rane, K.D., Sims, K.A. Citric acid production by Yarrowia lipolytica: Effect of nitrogen and biomass concentration on yield and productivity. Biotechnol Lett 18, 1139–1144 (1996). https://doi.org/10.1007/BF00128581

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