Abstract
A genomic clone containing the gl1–2 allele has been isolated and sequenced. The predicted amino acid sequence of the gl1–2 protein is identical to that of the GL1-Col allele up to position 201. At this point in the coding region of gl1–2 there is a deletion relative to the wild-type sequence that results in an in-frame stop codon at position 202. This deletion removes 27 amino acid residues, including a highly negatively charged region, from the predicted gl1–2 polypeptide. The loss of this negatively charged carboxy-terminal region from the gl1–2 product is most likely the cause of the partial loss of gene activity which results in a reduction in leaf trichome initiation.
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Esch, J.J., Oppenheimer, D.G. & Marks, M.D. Characterization of a weak allele of the GL1 gene of Arabidopsis thaliana . Plant Mol Biol 24, 203–207 (1994). https://doi.org/10.1007/BF00040586
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DOI: https://doi.org/10.1007/BF00040586