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Brain and Kidney Crosstalk

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Brain and Kidney Crosstalk

Abstract

Brain reaches everywhere that the neurons reach and controls the optimal functioning of all organs, including the kidneys, while normal functioning kidneys are quintessential for maintaining whole-body homeostasis, including neuronal homeostasis. Hence, brain injury [including traumatic brain injury, intracranial hemorrhage (ICH), subarachnoid hemorrhage, or ischemic stroke] may affect normal kidney functioning and in turn both acute kidney injury (AKI) and chronic kidney disease (CKD), as well as their treatment via renal replacement therapy (RRT) may inflict cerebral injury. These interactions often are bidirectional, a condition referred to as “Organ Crosstalk” (Nongnuch et al. 2014; Lu et al. 2015; Afsar et al. 2016).

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  1. Department of Neuroanaesthesia, Indraprastha Apollo Hospitals, New Delhi, India

    Nidhi Gupta

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  1. Nidhi Gupta
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  1. Department of Neuroanesthesiology & Critical Care, All India Institute of Medical Sciences, New Delhi, Delhi, India

    Hemanshu Prabhakar

  2. Department of Neuroanaesthesia & Critical Care, Indraprastha Apollo Hospital, New Delhi, Delhi, India

    Nidhi Gupta

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Gupta, N. (2020). Brain and Kidney Crosstalk. In: Prabhakar, H., Gupta, N. (eds) Brain and Kidney Crosstalk. Physiology in Clinical Neurosciences – Brain and Spinal Cord Crosstalks. Springer, Singapore. https://doi.org/10.1007/978-981-15-2325-0_3

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