Abstract
This article focuses on the surface treatment of medical grade cobalt–chromium alloy (ASTM-F75) by electric discharge machining (EDM) technique. The specimen’s surfaces were modified by EDM at a different combination of its significant performance parameters such as current and pulse on time to scrutinize the sample biological behavior. The cytocompatibility test with MTT assay in HeLa cell lines was employed to analyze the in-vitro biocompatibility of samples. The results demonstrated that the EDMed surface has significantly higher competent cell viability as compared to the untreated specimen. The surface engineering at 5 A current and high pulse on time (i.e., 200 µs) was found as significant parameters to achieve a highly favorable biocompatible surface. Therefore, the surface alteration of Co–Cr medical devices via EDM can be deemed as a promising technique for enhancing the surface properties of bioimplants.
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The authors thank IKG Punjab Technical University, Kapurthala, for its support to this research work.
Ethical approval No animal testing was performed during this study.
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Mahajan, A., Sidhu, S.S., Ablyaz, T. (2019). EDM Surface Treatment: An Enhanced Biocompatible Interface. In: Bains, P., Sidhu, S., Bahraminasab, M., Prakash, C. (eds) Biomaterials in Orthopaedics and Bone Regeneration . Materials Horizons: From Nature to Nanomaterials. Springer, Singapore. https://doi.org/10.1007/978-981-13-9977-0_3
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