Abstract
This paper implements bi-level discrete particle swarm optimization (BL-DPSO), an efficient discrete PSO variant for multiple sequence alignment (MSA) problem of nucleotides. Level one works on optimizing dimension for entire swarm, i.e., obtaining the optimal sequence length, whereas level two works for optimizing each and every particles position, i.e., to attain optimum gap positions for maximum alignment score. Set-theory based position and velocity update strategies are implemented in the proposed BL-DPSO. The capability of the proposed approach is evaluated with three standard scoring schemes at specific parameters with two types of benchmark datasets of DNA and RNA. BL-DPSO alignments are compared with four PSO variants, i.e., S-PSO, M-PSO, CPSO-S\(_k\), and TL-PSO, and two leading alignment software, i.e., ClustalW and T-Coffee, at different alignment scores. Obtained results prove the competency of BL-DPSO at accuracy aspects.
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References
Thompson, J.D., Higgins, D.G., Gibson, T.J.: CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673–4680 (1994)
Notredame, C., Higgins, D.G., Heringa, J.: T-Coffee: a novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302(1), 205–217 (2000)
Subramanian, A.R., Menkhoff, J.W., Kaufmann, M., Morgenstern, B.: DIALIGN-T: an improved algorithm for segment-based multiple sequence alignment. BMC Bioinformatics, 6(66), 2005
Durbin, R., Eddy, S., Krogh, A., Mitchison, G.: Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids. Cambridge University Press, United Kingdom (1998)
Lalwani, S., Kumar, R., Gupta, N.: A review on particle swarm optimization variants and their applications to multiple sequence alignment. J. Appl. Mathematics Bioinformatics 3(2), 87–124 (2013)
Kennedy, J.F., Eberhart, R.C.: Particle swarm optimization. In: Proceedings of IEEE International Conference on Neural Networks, Piscataway, NJ, pp. 1942–1948, 1995
Lalwani, S., Kumar, R., Gupta, N.: An efficient two-level swarm intelligence approach for multiple sequence alignment. Computing and Informatics 35, 1001–1023 (2016)
Lalwani, S., Kumar, R., Gupta, N.: An efficient two-level swarm intelligence approach for RNA secondary structure prediction with bi-objective minimum free energy scores. Swarm Evolutionary Comput. 27, 68–79 (2016)
Lalwani, S., Kumar, R., Gupta, N.: A study on inertia weight schemes with modified particle swarm optimization algorithm for multiple sequence alignment. In: 6th IEEE International Conference on Contemporary Computing, Noida, India, pp. 283–288 2013
Chellapilla K., Fogel G.B.: Multiple sequence alignment using evolutionary programming. In: Proceedings of the 1999 Congress on Evolutionary Computation, Washington DC, vol. 1, pp. 445–452 1999
Thompson, J.D., Plewniak, F., Poch, O.: A comprehensive comparison of multiple sequence alignment programs. Nucleic Acids Res. 27(13), 2682–2690 (1999)
Zablocki, F.B.R.: Multiple sequence alignment using Particle swarm optimization. Master’s thesis, Masters dissertation, University of Pretoria, 2007
Wilm, A., Mainz, I., Steger, G.: An enhanced RNA alignment benchmark for sequence alignment programs. Algorithms for Mol. Biol. 1(19), 2006
Acknowledgements
The first author (S.L.) gratefully acknowledges Science & Engineering Research Board, DST, Government of India for the fellowship (PDF/2016/000008).
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Lalwani, S., Sharma, H., Mohan, M.K., Deep, K. (2019). An Efficient Bi-Level Discrete PSO Variant for Multiple Sequence Alignment. In: Yadav, N., Yadav, A., Bansal, J., Deep, K., Kim, J. (eds) Harmony Search and Nature Inspired Optimization Algorithms. Advances in Intelligent Systems and Computing, vol 741. Springer, Singapore. https://doi.org/10.1007/978-981-13-0761-4_76
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DOI: https://doi.org/10.1007/978-981-13-0761-4_76
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