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ROS-Responsive Biomaterial Design for Medical Applications

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Biomimetic Medical Materials

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1064))

Abstract

Stimuli-responsive biomaterials undergo significant alterations in material structure and property in response to changes of local environmental factors (e.g. pH, temperature, enzyme activation, and water absorption). In particular, reactive oxygen species (ROS) is considered as a major stimulus because over-production of ROS involves most types of major pathogenesis. The application of ROS-responsive biomaterials requires suitable material designs to program user-defined changes of their structure and property in response to a sudden change in the local ROS level. This chapter summarizes the progress in designing and applying major types of ROS-responsive biomaterials within the past 10 years.

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Authors and Affiliations

  1. Department of Biomedical Science, Yonsei University College of Medicine, Seoul, South Korea

    Jung Bok Lee, Young Min Shin, Seo Yeon Kim & Hak-Joon Sung

  2. Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, South Korea

    Won Shik Kim

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  1. Jung Bok Lee
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  2. Young Min Shin
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  3. Won Shik Kim
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  4. Seo Yeon Kim
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  5. Hak-Joon Sung
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Correspondence to Hak-Joon Sung .

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  1. Seoul National University, Seoul, Korea (Republic of)

    Insup Noh

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Lee, J.B., Shin, Y.M., Kim, W.S., Kim, S.Y., Sung, HJ. (2018). ROS-Responsive Biomaterial Design for Medical Applications. In: Noh, I. (eds) Biomimetic Medical Materials. Advances in Experimental Medicine and Biology, vol 1064. Springer, Singapore. https://doi.org/10.1007/978-981-13-0445-3_15

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