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Introduction to Hair Development

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The Hair Fibre: Proteins, Structure and Development

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1054))

Abstract

The anagen phase of the hair follicle cycle is when the follicle is configured to grow hair. In short hairs (e.g., mouse underhairs and human eye lashes) anagen phase is short, but in the wool of sheep and in human scalp hair anagen is a prolonged state lasting for years. In this chapter we describe the morphological and biological divisions within the anagen follicle.

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References

  1. Langbein, L., et al. (2007). Novel type I hair keratins K39 and K40 are the last to be expressed in differentiation of the hair: Completion of the human hair keratin catalogue. Journal of Investigative Dermatology, 127, 1532–1535.

    Article  CAS  PubMed  Google Scholar 

  2. Bornschlögl, T., et al. (2016). Keratin network modifications lead to the mechanical stiffening of the hair follicle fiber. Proceedings of the National Academy of Sciences, 113(21), 5940–5945.

    Article  CAS  Google Scholar 

  3. Chapman, R. E., & Gemmell, R. T. (1971). Stages in the formation and keratinization of the cortex of the wool fiber. Journal of Ultrastructure Research, 36(3–4), 342–354.

    Article  CAS  PubMed  Google Scholar 

  4. Schneider, M. R., Schmidt-Ullrich, R., & Paus, R. (2009). The hair follicle as a dynamic miniorgan. Current Biology, 19(3), R132–R142.

    Article  CAS  PubMed  Google Scholar 

  5. Auber, L. (1951). The anatomy of follicles producing wool-fibres, with special reference to keratinization. Transactions of the Royal Society of Edinburgh, 62, 191–254.

    Article  Google Scholar 

  6. Baltenneck, F., et al. (2000). Study of the keratinization process in human hair follicle by X-ray microdiffraction. Cellular and Molecular Biology, 46(5), 1017–1024.

    PubMed  CAS  Google Scholar 

  7. Rafik, M. E., et al. (2006). In vivo formation steps of the hard α-keratin intermediate filament along a hair follicle: Evidence for structural polymorphism. Journal of Structural Biology, 154(1), 79–88.

    Article  CAS  PubMed  Google Scholar 

  8. Langbein, L., et al. (2001). The catalog of human hair keratins. II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins. Journal of Biological Chemistry, 276(37), 35123–35132.

    Article  CAS  PubMed  Google Scholar 

  9. Langbein, L., & Schweizer, J. (2005). Keratins of the human hair follicle. International Review of Cytology, 243, 1–78.

    Article  CAS  PubMed  Google Scholar 

  10. Mercer, E. H. (1961). Keratin and keratinization (1st ed., International series of monographs on pure and applied biology, Vol. 12, p. 316). Oxford: Pergamon Press.

    Google Scholar 

  11. Orwin, D. F. G., & Thomson, R. W. (1972). An ultrastructural study of the membranes of keratinizing wool follicle cells. Journal of Cell Science, 11(1), 205–219.

    PubMed  CAS  Google Scholar 

  12. Orwin, D. F., & Woods, J. L. (1982). Number changes and development potential of wool follicle cells in the early stages of fiber differentiation. Journal of Ultrastructure Research, 80(3), 312–322.

    Article  CAS  PubMed  Google Scholar 

  13. Orwin, D. F. G. (1976). Acid phosphatase distribution in the wool follicle. I. Cortex and fiber cuticle. Journal of Ultrastructure Research, 55, 312–324.

    Article  CAS  PubMed  Google Scholar 

  14. Orwin, D. F. G. (1979). The cytology and cytochemistry of the wool follicle. International Review of Cytology, 60, 331–374.

    Article  CAS  PubMed  Google Scholar 

  15. Marshall, R. C., Orwin, D. F. G., & Gillespie, J. M. (1991). Structure and biochemistry of mammalian hard keratin. Electron Microscope Reviews, 4(1), 47–83.

    Article  CAS  Google Scholar 

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Correspondence to Duane P. Harland .

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Harland, D.P. (2018). Introduction to Hair Development. In: Plowman, J., Harland, D., Deb-Choudhury, S. (eds) The Hair Fibre: Proteins, Structure and Development. Advances in Experimental Medicine and Biology, vol 1054. Springer, Singapore. https://doi.org/10.1007/978-981-10-8195-8_8

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