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Fenugreek Seed Mucilage Based Multiple Units for Oral Drug Delivery

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Plant Polysaccharides-Based Multiple-Unit Systems for Oral Drug Delivery

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Abstract

Fenugreek, also called as methi in Hindi and Bengali, is a legume plant, whose botanical name is Trigonella foenum-graecum L.; it belongs to the family: Leguminosae (Naidu et al. in LWT—Food Sci Technol 44:451–456, 2011; Nayak et al. in Indian J Pharm Educ Res 46:312–317 2012).

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References

  • A. Avachat, K.N. Gujar, V.B. Kotwal, S. Patil, Isolation and evaluation of fenugreek seed husk as a granulating agent. Indian J. Pharm. Sci. 69, 676–679 (2007)

    Article  CAS  Google Scholar 

  • Y.H. Chang, S.W. Cui, K.T. Roberts, P.K.W. Ng, Q. Wang, Evaluation of extrusion-modified fenugreek gum. Food Hydrocoll. 25, 1296–1301 (2011)

    Article  CAS  Google Scholar 

  • R. Dutta, A.K. Bandyopadhyay, Development of a new nasal drug delivery system of diazepam with natural mucoadhesive agent from Trigonella foenum-graecum L. J. Sci. Ind. Res. 64, 973–977 (2005)

    Google Scholar 

  • K. Gowthamarajan, K.T. Giriraj, A. Muthukumar, N. Mahadevan, M.K. Samanta, B. Suresh, Evaluation of fenugreek seed mucilage as gelling agent. Int. J. Pharm. Excip. 1, 16–19 (2002)

    Google Scholar 

  • H.M. Helmy, Study the effect of fenugreek seeds on gastric ulcer in experimental rats. World J. Dairy Food Sci. 6, 152–158 (2011)

    Google Scholar 

  • S. Kavirasan, G.H. Naik, R. Gangabhagirathi, C.V. Anuradha, K.I. Priyadarsini, in vitro studies on antiradical and antioxidant activities of fenugreek (Trigonella foenum-graecum) seeds. Food Chem. 103, 31–37 (2007)

    Article  Google Scholar 

  • G.T. Kulkarni, K. Gowthamarajan, Suresh B. Brahamajirao, Evaluation of binding properties of selected natural mucilages. J. Sci. Ind. Res. 61, 529–532 (2002)

    CAS  Google Scholar 

  • G.S. Kumar, A.K. Shetty, K. Sambaiah, P.V. Salimath, Antidiabetic property of fenugreek seed mucilage and spent turmeric in streptozotocin-induced diabetic rats. Nutr. Res. 25, 1021–1028 (2005)

    Article  CAS  Google Scholar 

  • V. Mathur, N. Mathur, Fenugreek and other less known legume galactomannan polysaccharides: scope for developments. J. Sci. Ind. Res. 64, 475–481 (2005)

    CAS  Google Scholar 

  • A. Mishra, A. Yadhav, S. Pal, A. Singh, Biodegradable graft copolymers of fenugreek mucilage and polyacrylamide: a renewable reservoir to biomaterials. Carbohydr. Polym. 65, 58–63 (2006)

    Article  CAS  Google Scholar 

  • M.R. Mundhe, R.R. Pagore, K.R. Biyani, Isolation and evaluation of Triginella foenum-gracum mucilage as gelling agent in diclofenac potassium gel. Int. J. Ayur. Herb. Med. 2, 300–306 (2012)

    Google Scholar 

  • M.M. Naidu, B.N. Shyamala, J.P. Naik, G. Sulochanamma, P. Srinivas, Chemical composition and antioxidant activity of the husk and endosperm of fenugreek seeds. LWT—Food Sci. Technol. 44, 451–456 (2011)

    Google Scholar 

  • A.K. Nayak, D. Pal, J. Pradhan, T. Ghorai, The potential of Trigonella foenum-graecum L. seed mucilage as suspending agent. Indian J. Pharm. Educ. Res. 46, 312–317 (2012)

    Google Scholar 

  • A.K. Nayak, D. Pal, Trigonella foenum-graecum L. seed mucilage-gellan mucoadhesive beads for controlled release of metformin HCl. Carbohydr. Polym. 107, 31–40 (2014)

    Article  CAS  Google Scholar 

  • A.K. Nayak, D. Pal, S. Das, Calcium pectinate-fenugreek seed mucilage mucoadhesive beads for controlled delivery of metformin HCl. Carbohydr. Polym. 96, 349–357 (2013a)

    Article  CAS  Google Scholar 

  • A.K. Nayak, D. Pal, J. Pradhan, M.S. Hasnain, Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation. Int. J. Biol. Macromol. 54, 144–154 (2013b)

    Article  CAS  Google Scholar 

  • M. Nitalikar, P.A. Patil, S.P. Dhole, D.M. Sakarkar, Evaluation of fenugreek seed husk as tablet binder. Int. J. Pharm. Res. Rev. 2, 21–23 (2010)

    Google Scholar 

  • A. Nokhodchi, A. Nazemiyeh, A. Khodaparast, T. Sorkh-Shahan, H. Valizadeh, J.L. Ford, An in vitro evaluation of fenugreek mucilage as a potential excipient for oral controlled-release matrix tablet. Drug Dev. Ind. Pharm. 34, 323–329 (2008)

    Article  CAS  Google Scholar 

  • G.A. Petropoulos, Fenugreek: the genus Trigonella, in Botany, ed. by G.A. Petropoulos (Taylor and Francis, London, 2002), pp. 9–17

    Google Scholar 

  • S. Riad, A.A. El-Baradie, Fenugreek mucilage and its relation to the reputed laxative action of this seed. Egyptian J. Chem. 2, 163–168 (1959)

    CAS  Google Scholar 

  • V. Sabale, V. Patel, A. Paranjapel, P Sabale, Isolation of fenugreek seed mucilage and its comparative evaluation as a binding agentwith standard binder. Int. J. Pharm. Res. 1, 56–62 (2009)

    Google Scholar 

  • R.D. Sharma, T.C. Raghuram, N.S. Rao, Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur. J. Clin. Nutr. 44, 301–306 (1990)

    CAS  Google Scholar 

  • G. Sindhu, M. Ratheesh, G.L. Shyni, B. Nambisan, A. Helen, Anti-inflammatory and antioxidative effects of mucilage Trigonella foenum-graecum (Fenugreek) on adjuvant induced arthritic rats. Int. Immunopharmacol. 12, 205–211 (2012)

    Article  CAS  Google Scholar 

  • S. Sukhavasi, V.S. Kishore, Formulation and evaluation of fast dissolving tablets of amlodipine besylate by using fenugreek seed mucilage and Ocimum basilicum gum. Int. Curr. Pharm. J. 1, 243–249 (2012)

    Article  CAS  Google Scholar 

  • I.K. Yadhav, D.A. Jain, Design and development of Triginella foenum-gracum seed mucilage based matrix tablets of diclofenac sodium. World J Pharm. Res. 1, 1170–1182 (2012)

    Google Scholar 

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Correspondence to Amit Kumar Nayak .

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Nayak, A.K., Hasnain, M.S. (2019). Fenugreek Seed Mucilage Based Multiple Units for Oral Drug Delivery. In: Plant Polysaccharides-Based Multiple-Unit Systems for Oral Drug Delivery. SpringerBriefs in Applied Sciences and Technology. Springer, Singapore. https://doi.org/10.1007/978-981-10-6784-6_8

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