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Exosomes as Diagnostic Biomarkers in Cardiovascular Diseases

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Exosomes in Cardiovascular Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 998))

Abstract

Exosomes play important roles in the development and progression of cardiovascular diseases by modulating intercellular communication. Contents and quantities of exosomes are variable under different pathological cardiovascular conditions. Based on these concepts, exosomes have been proposed as novel diagnostic biomarkers in cardiovascular diseases. However, many issues related with clinically applicable biomarkers remain unresolved. Within this chapter, we discuss the potential value, but also the current challenges using exosome numbers and contents as diagnostic and prognostic biomarker in diverse cardiovascular pathologies.

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Author notes

  1. Felix Jansen and Qian Li contributed equally to this work.

Authors and Affiliations

  1. Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany

    Felix Jansen & Qian Li

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  1. Felix Jansen
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  2. Qian Li
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Corresponding author

Correspondence to Felix Jansen .

Editor information

Editors and Affiliations

  1. Shanghai University , Shanghai, China

    Junjie Xiao

  2. Victor Babeş National Institute of Patho , Bucharest, Romania

    Sanda Cretoiu

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Jansen, F., Li, Q. (2017). Exosomes as Diagnostic Biomarkers in Cardiovascular Diseases. In: Xiao, J., Cretoiu, S. (eds) Exosomes in Cardiovascular Diseases. Advances in Experimental Medicine and Biology, vol 998. Springer, Singapore. https://doi.org/10.1007/978-981-10-4397-0_4

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