Skip to main content

Industrial Proteins Produced from Transgenic Plants

  • Chapter
Plants as Factories for Protein Production

Abstract

Industrial proteins include those used for industrial applications such as purification, diagnostics and enzymes for industrial processes. Enzymes as natural products are obtained from animal, plant and/or microbial tissues. When the industrial enzyme business began, enzymes were primarily obtained from plant and animal sources. However, today the bulk of commercial enzymes are derived from microbial sources either natural or recombinant. As a result, the extraction of commercial enzymes from plant and animal tissue has declined in recent years and continues to decline.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Archer DB. 1994. Enzyme production by recombinant Aspergillus. Bioprocess Technol. 19: 373–393.

    PubMed  CAS  Google Scholar 

  • Bowden GA, Paredes AM and Georgious G. 1991. Structure and morphology of protein inclusion bodies in Escherichia coli. Biotechnology 9: 725–730.

    Article  PubMed  CAS  Google Scholar 

  • Caramelo L, Martinez MJ and Martinez AT. 1999. A search for lignolytic peroxidases in the fungus Pleurotus eryngii involving alpha-keto-gamma thiomethylbutyric acid and lignin model dimers. Appl. Env. Micro. 65: 916-922.

    Google Scholar 

  • Dai Z, Hooker BS, Anderson DB and Thomas SR. 2000. Improved plant-based production of El endoglucanase using potato: expression optimization and tissue targeting. Molecular Breeding 6: 277–285.

    Article  CAS  Google Scholar 

  • DeJong E, de Vries FP, Field JA, van der Zwan RP and de Bont JAM. 1992. Isolation and screening of basidiomycetes with high peroxidative activity. Mycol. Res. 96: 10981104.

    Google Scholar 

  • Fiedler U, Phillips J, Artsaenko O and Conrad U. 1997. Optimization of scFv antibody production in transgenic plants. Immunotechology 3: 205–216.

    Article  CAS  Google Scholar 

  • Harashima S. 1994. Heterologous protein production by yeast host-vector systems. Bioprocess Techol. 19: 137–158.

    CAS  Google Scholar 

  • Herbers K, Wilke 1 and Sonnewald U. 1995. A thermostable xylanase from Clostridium thermocellum expressed at high levels in the apoplast of transgenic tobacco has no detrimental effects and is easily purified. Bio/technology, Bio/technology. 13: 63–66.

    CAS  Google Scholar 

  • Hood E and Howard J. 1999. Protein products from transgenic plants. Agro-Food-Industry Hi-Tech, 3, 10: 35–36

    Google Scholar 

  • Hood EE, Kusnadi A, Nikolov Z and Howard, JA. 1999. Molecular farming of industrial proteins from transgenic maize. Chemicals via Higher Plant Bioengineering, pp. 127147.

    Google Scholar 

  • Hood EE and Jilka JM. 1999. Plant-based production of xenogenic proteins. Current Opinion in Biotechnology 10: 382–386.

    Article  PubMed  CAS  Google Scholar 

  • Hood EE, Witcher DR, Maddock S, Meyer T, Baszczynski C, Bailey M, Flynn P, Register J, Marshall L, Bond D, Kulisek E, Kusnadi A, Evangelista R, Nikolov Z, Wooge C, Mehigh RJ, Hernan R, Kappel WK, Ritland D, Li CP and Howard JA. 1997. Commercial production of avidin from transgenic maize: Characterization of transformant, production, processing, extraction and purification. Molecular Breeding 3: 291–306.

    Article  CAS  Google Scholar 

  • Janse BJH, Gaskell J, Akhtar M and Cullen D. 1998. Expression of Phanerochaete chrysosporium genes encoding lignin peroxidases, manganese peroxidases, and glyoxal oxidase in wood. Appl. Env. Microbiol. 64: 3536–3538.

    CAS  Google Scholar 

  • Jensen LG, Olsen O, Kops O, Wolf N, Thomsen KK and von Wettstein D. 1996. Transgenic barley expressing a protein-engineered, thermostable (1,3-1,4)-β-glucanase during germination. Proc. Natl. Acad. Sci. USA 93: 3487–3491.

    Article  PubMed  CAS  Google Scholar 

  • Jilka J, Hood EE, Dose R and Howard J. 1999. The benefits of proteins produced in transgenic plants. AgBiotechNet. 1:1-4.

    Google Scholar 

  • Kunitz M and Northrop JH. 1936. Isolation from beef pancreas of crystalline trypsinogen, trypsin, a trypsin inhibitor, and an inhibitor-trypsin compound. J. Gen. Physiol., 19: 991–1007.

    Article  PubMed  CAS  Google Scholar 

  • Leite A, Kemper EL, da Silva MJ, Luchessi AD, Siloto RMP, Bonaccorsi ED, El-Dorry HF and Arruda P. 2000. Expression of correctly processed human growth hormone in seeds of transgenic tobacco plants. Molecular Breeding 6: 47–53.

    Article  CAS  Google Scholar 

  • Liu J-H, Selinger LB, Cheng K-J, Beauchemin KA and Moloney MM. 1997. Plant seed oil-bodies as an immobilization matrix for a recombinant xylanase from the rumen fungus Neocallimastix patriciarum. Molecular Breeding 3: 463–470.

    Article  CAS  Google Scholar 

  • Moloney MM, Walker JM and Sharma KK. 1989. High efficiency transformation of Brassica napus usingAgrobacterium vectors. Plant Cell Reports 8: 238–242.

    Article  CAS  Google Scholar 

  • Patel M, Johnson JS, Brettell RIS, Jacobsen J and Xue G-P. 2000. Transgenic barley expressing a fungal xylanase gene in the endosperm of the developing grains. Molecular Breeding 6: 113–123.

    Article  CAS  Google Scholar 

  • Pen J, Molendijk L, Quax WJ, Sijmons PC, van Ooyen AJJ, van den Elzen PJM, Rietveld K and Hoekema A. 1992. Production of active bacillus licheniformis alpha-amylase in tobacco and its application in starch liquefaction. Bio/Technol, 10: 292–296.

    Article  CAS  Google Scholar 

  • Takaiwa F, Tada Y, Wu C-Y, Washida H and Utsumi S. 2000. High level accumulation of soybean glycinin in rice endosperm. Plant Mol. Biol. Rptr. Supplement 18: 2: S28–28.

    Google Scholar 

  • Van Rooijen GJH and Moloney M. 1995. Plant seed oil-bodies as carriers for foreign proteins. BioTechnology, 13: 72–77.

    Article  PubMed  Google Scholar 

  • Verwoerd TC, van Paridon PA, van Ooyen AJJ, van Lent JWM, Hoekema A and Pen J. 1995. Stable accumulation of Aspergillus niger phytase in transgenic tobacco leaves. Plant Physiol. 109: 1199–1205.

    Article  PubMed  CAS  Google Scholar 

  • Witcher DR, Hood EE, Peterson D, Bailey M, Bond D, Kusnadi A, Evangelista R, Nikolov Z, Wooge C, Mehigh R, Kappel W, Register JC and Howard J. 1998. Commercial production of β-glucuronidase (GUS): A model system for the production of proteins in plants. Molecular Breeding 4: 301–312.

    Article  CAS  Google Scholar 

  • Zhong GY, Peterson D, Delaney DE, Bailey M, Witcher DR, Register III JC, Bond D, Li C-P, Marshall L, Kulisek E, Ritland D, Meyer T, Hood EE and Howard JA. Commercial production of aprotinin in transgenic maize seeds. Molecular Breeding_ 5: 345–356, 1999.

    Article  CAS  Google Scholar 

  • Ziegelhoffer T, Will J, and Austin-Phillips S. 1999. Expression of bacterial cellulase genes in transgenic alfalfa (Medicago sativa L.), potato (Solanum tuberosum L.) and tobacco (Nicotiana tabacum L.). Molecular Breeding 5: 309–318.

    Article  CAS  Google Scholar 

  • Ziegler MT, Thomas SR, and Danna KJ. 2000. Accumulation of a thermostable endo-l,4-ß-Dglucanase in the apoplast of Arabidopsis thaliana leaves. Molecular Breeding 6: 37–46.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Hood, E.E., Woodard, S.L. (2002). Industrial Proteins Produced from Transgenic Plants. In: Hood, E.E., Howard, J.A. (eds) Plants as Factories for Protein Production. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2693-1_6

Download citation

  • DOI: https://doi.org/10.1007/978-94-017-2693-1_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-6113-3

  • Online ISBN: 978-94-017-2693-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics