Abstract
Since the pioneering work of Rapkine (1931) the hypothesis that many rhythmic life processes may involve cyclic interconversion of dithiols to disulphides provides a central theme that unifies ultradian, cell division cycle and circadian rhythm research. We have shown that in an autonomously-oscillating continuous culture of Saccharomyces cerevisiae ultradian (τ = 40 min) cycles between high and low respiratory states are accompanied by redox cycling of nicotinamide nucleotide(s) and glutathione. This system may provide insights into regulation of rhythmic processes with longer periods.
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Lloyd, D., Murray, D.B. (2000). Redox Cycling of Intracellular Thiols: State Variables for Ultradian, Cell Division Cycle and Circadian Cycles?. In: Driessche, T.V., Guisset, JL., Petiau-de Vries, G.M. (eds) The Redox State and Circadian Rhythms. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9556-8_5
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DOI: https://doi.org/10.1007/978-94-015-9556-8_5
Publisher Name: Springer, Dordrecht
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