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The use of SPECT in the analysis of brain tumours

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SPECT Imaging of the Brain

Part of the book series: Developments in Nuclear Medicine ((DNUM,volume 29))

Abstract

Despite advances in the treatment and prognosis of many solid tumours over the last 20 years, the outcome for adults with malignant primary brain tumours remains very poor. The incidence is reported at approximately 6–7 per 100000 of the population. The West of Scotland (the catchment areas of the Glasgow Institute of Neurological Sciences) has a population of 2.7 million. This means that 120 to 150 new cases present each year.

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References

  1. Kim TS, Halliday AL, Hedley-White ET, Convery K. Correlates of survival and the Daumas-Duport grading system for astrocytomas. J Neurosurg. 1991;74:27–37.

    Article  PubMed  CAS  Google Scholar 

  2. Chang CH. Comparison of post operative radiotherapy and combined post operative radiotherapy and chemotherapy in the multidisciplinary management of malignant glioma. Cancer. 1983;52:937–1007.

    Article  Google Scholar 

  3. Bloom HJG. Intracranial tumors: response and resistance to therapeutic endeavours 1970-1980. Int J Radiat Oncol Biol Phys. 1982;8:1083–1113.

    Article  CAS  Google Scholar 

  4. Stenning SP, Freedman LS, Bleehan NM. An overview of published results from randomised studies of nitrosourease in primary high grade malignant gliomas. Br J Cancer. 1987;56:89–90.

    Article  PubMed  CAS  Google Scholar 

  5. Albert FK, Forsting M, Sartor K, Adams H-P, Kunze S. Early post-operative magnetic resonance imaging after resection of malignant glioma objective evaluation of residual tumour and its influence on regrowth and prognosis. Neurosurg. 1994;34:445–461.

    Google Scholar 

  6. Hochberg F, Pruitt A. Assumptions in the radiotherapy of glioma. Neurology. 1980;30:997–999.

    Google Scholar 

  7. Fertil B, Malaise E. Intrinsic radiosensitivity of human cell lines is correlated with radio-sensitivity analysis of 101 published survival curves. Int J Radiat Oncol Biol Phys. 1985; 11:699–707.

    Article  Google Scholar 

  8. Steel GG, Peacock JH. Why are some human tumors more radiosensitive than others? Radio-ther Oncol. 1989;15:63–72.

    Article  CAS  Google Scholar 

  9. Tahian A, Budach J, Freeman D, Giono H, Smit H, Steele E. In vivo radiation sensitivity of glioblastoma multiforme. J Neuro-oncol. 1994; 19:179.

    Google Scholar 

  10. Taghan A, Ramsay J, Allalunis-Turner J, et al. Intrinsic radiation sensitivity may not be the major determinant of the poor clinical outcome of glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 1993;25:243–249.

    Article  Google Scholar 

  11. Hoshino T, Barker M, Wilson L. Cell kinetics of human gliomas. J Neurosurg. 1972;37:15–26.

    Article  PubMed  CAS  Google Scholar 

  12. Nagashima TS, DeArmond S, Murcovic J. Immunocytochemical demonstration of S-phase cells by anti-bromodeoxuridine monoclonal antibody in human brain tumour tissues. Acta Neuropathol. 1985;67:155–159.

    Article  PubMed  CAS  Google Scholar 

  13. Atkins HL, Budinger TE, Labowitz E. Thallium201 for medical use. Part 3: Human distribution of physical imaging properties. J Nucl Med. 1977;18:133–140.

    PubMed  CAS  Google Scholar 

  14. Ancri D, Bassett JY, Lonchampt MF, Etarard C. Diagnosis of cerebral lesions by thallium201. J Nucl Med. 1978;128:417–422.

    CAS  Google Scholar 

  15. Kaplan WD, Takronan T, Morris JH, Rumbough CL, Connolly BT, Atkins HL. Thallium201 brain tumor imaging: a comparative study with pathologic correlation. J Nucl Med. 1987;28: 47–52.

    PubMed  CAS  Google Scholar 

  16. Kim KT, Black KL, Marciano D. Thallium201 SPECT imaging of brain tumors: methods and results. J Neurosurg. 1989;71:342–346.

    Article  PubMed  Google Scholar 

  17. Ueda T, Kaji Y, Wakisaka S. Time sequential single photon emission computed tomography studies in brain tumour using thallium-201. Eur J Nucl Med. 1993;20:138–145.

    Article  PubMed  CAS  Google Scholar 

  18. Jinnouchi S, Hoshi H, Ohnishi T, et al. Thallium-201 SPECT for predicting histological types of meningiomas. J Nucl Med. 1993;34:2091–2094.

    PubMed  CAS  Google Scholar 

  19. Schwartz RB, Carvalho PA, Alexander E, Loeffler JS, Folkerth R, Holman BL. Radiation necrosis vs high-grade recurrent glioma: Differentiation by using dual-isotope SPECT with 201T1 and 99m Tc-HMPAO. Am J Neuroradiol. 1991;12:1187–1192.

    PubMed  CAS  Google Scholar 

  20. Kubota R, Kubota K, Yamada S. Methionine uptake by tumor tissue: a microautoradiographic comparison with FDG. J Nucl Med. 1995;36:484–492.

    PubMed  CAS  Google Scholar 

  21. Britton J, Blank M. Thallium activation of the (Na+K+) activated ATPase of rabbit kidney. Biochem Biophys Acta. 1968;159:160–166.

    Article  Google Scholar 

  22. Tonami N, Hisada K. Thallium201 SPECT in the evaluation of gliomas. J Nucl Med. 1993; 34:2089–2090.

    PubMed  CAS  Google Scholar 

  23. Whittle I. The biology of glioma. In: Teasdale GM, Miller JD, editors. Current Neurosurgery. Churchill Livingstone, 1992:255–284.

    Google Scholar 

  24. Lopez M, Van Den Berg S, Scheithauer B. The World Health Organisation classification system of nervous system tumours in experimental neuro-oncology. In: Levine AJ, Schmidek HH, editors. Molecular genetics of nervous system tumours. New York: Wiley Liss, 1993:1–36.

    Google Scholar 

  25. Black KL, Hawkins RA, Kim KT, Becker DP, Lerner C, Marciano D. Use of Thallium201 (SPECT) to quantitate malignancy grade of glioma. J Neurosurg. 1989;71:342–346.

    Article  PubMed  CAS  Google Scholar 

  26. Francavilla T, Miletich R, Di Chiro G. Positron Emission Tomography in the detection of malignant degeneration of low-grade gliomas. Neurosurg. 1989;24:1–5.

    Article  CAS  Google Scholar 

  27. Mountz JM, Stafford-Schuck M, McIver PE. Thallium201 tumour/cardiac ratio estimation of residual astrocytoma. J Neurosurg. 1988;68:705–709.

    Article  PubMed  CAS  Google Scholar 

  28. Ancri D, Bassett JY. Diagnosis of cerebral metastases by Thallium201. Br J Radiol. 1980; 53:443–445.

    Article  PubMed  CAS  Google Scholar 

  29. Vertosick FT, Selker RG, Grossman SJ, Joyse JM. Correlation of Thallium201 single photon emission computed tomography and survival after treatment failure in patients with glioblastoma multiforme. Neurosurg. 1994;34(3):396–401.

    Article  Google Scholar 

  30. Piepmeier JM. Observations on the current treatment of low grade astrocytic tumors of the cerebral hemispheres. J Neurosurg. 1987;67:177–81.

    Article  PubMed  CAS  Google Scholar 

  31. O’Tuama LA, Treves ST, Larar JN, Packard AB, Kwan AJ, Barnes PD. Thallium201 versus Technetium-99m-MIBI SPECT in evaluation of childhood brain tumors: A within-subject comparison. J Nucl Med. 1993;34:1045–1051.

    PubMed  Google Scholar 

  32. Levivier M, Goldman S, Pirotte B, et al. Diagnostic yield of stereotactic brain biopsy guided by positron emission tomography with [18F]Fluorodeoxyglucose. J Neurosurg. 1995;82: 445–452.

    Article  PubMed  CAS  Google Scholar 

  33. Mosskin M, Ericson K. Positron Emission Tomography compared with magnetic resonance imaging and computed tomography in supratentorial gliomas using multiple stereotactic biopsies as reference. Acta Radiologica. 1989;30:225–232.

    Article  PubMed  CAS  Google Scholar 

  34. Maciunas RJ, Kessler RM, Maurer C, Mandava V, Watt G. Positron emission tomography image directed stereotactic neurosurgery. Stereotact Funct Neurosurg. 1992;58:134–40.

    Article  PubMed  CAS  Google Scholar 

  35. Hughes SW, Sofat A, Kitchen ND, et al. Computer planning of stereotactic iodine-125 seed brachytherapy for recurrent malignant gliomas. Br J Radiol. 1995;68:175–181.

    Article  PubMed  CAS  Google Scholar 

  36. Drake J, Rutka J, Hoffman H. ISG Viewing Wand System. Neurosurg. 1994;34:1094–1095.

    Article  Google Scholar 

  37. Kelly D, Hunt C. The limited value of cytoreductive surgery in elderly patients with malignant gliomas. Neurosurg. 1994;34:62–67.

    Article  CAS  Google Scholar 

  38. Tjuvajev KG, Abrams DJ, Finn RG, Blasberg RG. Imaging brain tumours with non-metabolised amino acids: advantages over fluorodeoxyglucose (FDG). J Cereb Blood Flow Metab. 1993;13:S572.

    Google Scholar 

  39. Oldendorf WH. Saturation of amino acid uptake by human brain tumour demonstrated by SPECT. J Nucl Med. 1991;32:1229–1230.

    PubMed  CAS  Google Scholar 

  40. Langen K-J, Goenen HH, Roosen N. SPECT studies of brain tumours with L = 3-[123I] Iodo-(-Methyl Tyrosine): Comparison with PET, 124IMT and first clinical results. J Nucl Med. 1990;31:281–286.

    PubMed  CAS  Google Scholar 

  41. Cruickshank GS, Rampling RP, Cowans W. Direct measurement of the pO2 distribution in human malignant brain tumours. Adv Exp Med Biol. 1993;345:465–470.

    Article  Google Scholar 

  42. Groshar D, McEwan JB, Parliament MB, et al. Imaging tumour hypoxia and tumour perfusion. J Nucl Med. 1993;34:885–888.

    PubMed  CAS  Google Scholar 

  43. Khalifa A, Rampling R, Patterson J, Murray T, Kerr D. Investigation of the uptake and distribution of Irridium111 labelled liposomes in relapsed high grade astrocytoma. JNNP. 1995;59:204.

    Google Scholar 

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Authors
  1. Garth S. Cruickshank
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Editor information

Editors and Affiliations

  1. Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland

    Roderick Duncan

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© 1997 Springer Science+Business Media Dordrecht

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Cruickshank, G.S. (1997). The use of SPECT in the analysis of brain tumours. In: Duncan, R. (eds) SPECT Imaging of the Brain. Developments in Nuclear Medicine, vol 29. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5398-0_6

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  • DOI: https://doi.org/10.1007/978-94-011-5398-0_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6271-8

  • Online ISBN: 978-94-011-5398-0

  • eBook Packages: Springer Book Archive

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