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Ultrafiltration in peritoneal dialysis

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The Textbook of Peritoneal Dialysis

Abstract

There is a clinical requirement to remove excess body water, electrolytes, and other uremic toxins on a regular basis from patients with end-stage renal failure. During extracorporeal artificial kidney treatment, fluid is removed by simply applying a difference in hydrostatic or hydraulic pressure across the synthetic membrane. This approach is impractical during peritoneal dialysis; instead, fluid is removed from the patient by creating a difference in osmotic pressure between dialysis solution and blood. Thus, fluid removal during peritoneal dialysis is primarily by osmosis and is commonly referred to as osmotic ultrafiltration (or simply ultrafiltration) because of the similarities between transmembrane fluid movement by osmosis and ultrafiltration [1]. We will focus in this chapter on describing both the driving forces that move fluid across the peritoneum and the rate of solute transport that accompanies this transperitoneal fluid movement.

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Authors
  1. John K. Leypoldt
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  2. Chandra D. Mistry
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Editors and Affiliations

  1. Department of Renal Medicine, Manchester Royal Infirmary, Manchester, UK

    Ram Gokal

  2. Division of Nephrology, Department of Internal Medicine, School of Medicine, University of Missouri, Health Sciences Center and Dalton Cardiovascular Research Center, Columbia, Missouri, USA

    Karl D. Nolph

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Leypoldt, J.K., Mistry, C.D. (1994). Ultrafiltration in peritoneal dialysis. In: Gokal, R., Nolph, K.D. (eds) The Textbook of Peritoneal Dialysis. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0814-0_6

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  • DOI: https://doi.org/10.1007/978-94-011-0814-0_6

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