Skip to main content

In vivo inhibition of pmn migration by antimacrophage serum

  • Chapter
Inflammation: Mechanisms and Treatment

Abstract

The aim of the present investigation was to evaluate the effect of rabbit anti-rat macrophage serum (AMS) on the oedema and cell migration induced by a preparation of M. tuberculosis. Inflammation induced by M. tuberculosis is known to recruit macrophages, and anti-macrophage serum was found to affect macrophages in vitro as well in vivo, and is becoming a valuable tool to study their various functions1–4.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Unanue, E. R. (1968). Properties and some uses of antimacrophage antibodies. Nature (London), 218, 36

    Article  CAS  Google Scholar 

  2. Hirsh, M. S., Gary, G. W. Jr. and Murphy, F. A. (1969). In vitro and in vivo properties of antimacrophage sera. J. Immunol., 102, 656

    Google Scholar 

  3. Argyris, B. F. and Plotikin, D. H. (1969). Effect of antimacrophage serum on antibody production and phagocytosis in mice. J. Immunol., 103, 372

    PubMed  CAS  Google Scholar 

  4. Gallily, R. (1971). In vitro and m vivo studies of the properties and effects of an ti-macrophage sera (AMS). Clin. Exp. Immunol., 9, 381

    PubMed  CAS  Google Scholar 

  5. Coons, A. H. and Kaplan, M. H. (1950), Localization of antigen in tissues cells. II. Improvements in a method for the detection of antigen by means of a fluorescent antibody. J. Exp. Med., 91, 1

    Article  PubMed  CAS  Google Scholar 

  6. Ribeiro des Santos, R. S. and Hudson, L. (1980). Trypanosoma cruzi: Binding of parasite antigens to mammalian cell membranes. Parasite Immunol., 2, 1

    Article  Google Scholar 

  7. Bøyum, A. (1976). Isolation of lymphocytes, granulocytes and macrophages. Scand. J. Immunol., 5, (Suppl. 5),

    Google Scholar 

  8. Stuart, A. E., Habeshaw, J. A. and Davidson, E. A. (1978). Phagocytes in vitro. In Weir, D.M. (ed.) Handbook of Experimental Immunology, Vol. 2. Cellular Immunology, pp. 1–30. (Oxford: Blackwell Scientific)

    Google Scholar 

  9. Ouchterlony, Ö (1958). Diffusion in gel methods for immunological analysis. Prog. Allergy, 5, 1

    PubMed  CAS  Google Scholar 

  10. Wadsworth, A., Maltaner, E. and Maltaner, F. (1931). The quantitative determination of the fixation of complement by the imune serum antigen. J. Immol., 21, 241

    Google Scholar 

  11. Ferreira, S. H. (1979). A new method for measuring variations of rat paw. J. Pharm. Pharmacol., 31, 649

    Article  Google Scholar 

  12. Chalkley, H. W-. (1943). Method for the quantitative morphologic analysis of tissues. J. Natl. Cancer Inst., 4, 47

    Google Scholar 

  13. Feldman, J. D., Tubergen, D. G., Pollock, E. M. and Unanue, E. R. (1972). Distribution of a macrophage specific antigen. Cell. Immunol., 5, 325

    Article  PubMed  CAS  Google Scholar 

  14. Jennings, J. F. and Hughes, L. A. (1969). Inhibition of phagocytosis by anti-macrophage antibodies. Nature (London), 221, 79

    Article  CAS  Google Scholar 

  15. Jasin, H.E., Lennard, D. and Ziff, M. (1971). Studies on antimacrophage globulin. Clin. Exp. Immunol., 8, 801

    PubMed  CAS  Google Scholar 

  16. Despont, J.P. and Cruchaud, A. (1969). In vivo and in vitro effects of anti-macrophage serum. Nature (London), 223, 838

    Article  CAS  Google Scholar 

  17. Kazmierowski, J. A., Gallin, J. I. and Reynolds, H. Y. (1977). Mechanism for the inflammatory responses in primate lungs. Demonstration and partial characterization of an alveolar macrophage-derived chemotactic factor with preferential activity for polymorphonuclear. J. Clin. Invest., 59, 273

    Article  PubMed  CAS  Google Scholar 

  18. Ferreira, S. H. (1980). Are macrophages the body’s alarm cells? Agents Actions, 10, 229

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1980 MTP Press Limited

About this chapter

Cite this chapter

Ferreira, S.H., De Souza, G.E.P., Ribeiro Dos Santos, R. (1980). In vivo inhibition of pmn migration by antimacrophage serum. In: Willoughby, D.A., Giroud, J.P. (eds) Inflammation: Mechanisms and Treatment. Inflammation: Mechanisms and Treatment, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9423-8_114

Download citation

  • DOI: https://doi.org/10.1007/978-94-010-9423-8_114

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-9425-2

  • Online ISBN: 978-94-010-9423-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics