Abstract
The behavior of the synaptonemal complex (SC) during synapsis in duplication and inversion heterozygotes has been studied mainly in surface spreads of mouse spermatocytes (Poorman et al., 1981a, b; Moses and Poorman, 1981; Davisson et al., 1981; Moses et al., 19821 Two phases of synapsis (i.e., SC formation) have been revealed: the first, at zygotene, is restricted to homologous regions (homosynapsis); the second occurs during pachytene, is indifferent to homology and permits SC formation between nonhomologous regions (heterosynapsis). The transition between the two phases is not ordinarily recognized during synapsis because the “straight” SCs normally formed at zygotene are stable and pass through the second, homology-indifferent phase unchanged. Rearrangement configurations (duplication buckles and inversion loops) of SC’s formed at zygotene undergo alterations that result at the end of pachytene in straight, normal-appearing SC’s nonhomologously synapsed in the rearrangement regions. This process of change has been termed “synaptic adjustment” (review: Moses, 1981).
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© 1984 The Organising Committee of the VIII International Chromosome, Conference, Lübeck
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Moses, M.J., Poorman, P.A. (1984). Synapsis, synaptic adjustment and DNA synthesis in mouse oocytes. In: Bennett, M.D., Gropp, A., Wolf, U. (eds) Chromosomes Today. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-9163-3_9
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DOI: https://doi.org/10.1007/978-94-010-9163-3_9
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