Abstract
When blood or plasma is brought into contact with certain surfaces, such as glass, kaolin, and celite, it acquires the capacity to accelerate clotting. This surface activation does not occur in the blood of patients with deficiency of Hageman factor (factor xii) or plasma thromboplastin antecedent (factor xi).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Alkjaersig, N., A. P. Fletcher, S. Sherry, The mechanism of clot dissolution by plasmin. J. clin. Invest. 38, 1086 (1959).
Biggs, R., A. A. Sharp, J. Margolis, R. M. Hardisty, J. Stewart, W. M. Davidson, Defects in the early stages of blood coagulation A report of four cases. Brit. J. Haemat. 4, 177 (1958)•
Didisheim, P., Panel Discussion. Xth Congress of the International Society of Haematology, Stockholm (1964).
Dudok de Wit, C., H. W. Krijnen, G. J. H. den Ottolander, The measurement of fibrinolytic activity with 131J labeled clots. I: Methods. Thrombos. Diathes. haemorrh. (Stuttg.) 8, 315 (1962).
Haanen, C., F. Hommes, H. Benraad, G. Morselt, A case of Hageman factor deficiency and a method to purify the factor. Thrombos. Diathes. haemorrh. (Stuttg.) 5, 201 (1960).
Haanen, C., F. Hommes, G. Morselt, Some observations on the role of Hageman factor in blood coagulation. Thrombos. Diathes. haemorrh. (Stuttg.) 6, 261 (1861).
Haanen, C., J. G. G. Schoenmakers, One-stage assay for Hageman factor (factor xn). Further studies on the role of Hageman factor in blood coagulation. Thrombos. Diathes. haemorrh. (Stuttg.) 9, 557 (1963).
Haanen, C., G. Morselt and J. Schoenmakers, Contact activation of Hageman factor and the interaction of Hageman factor and plasma thromboplastin antecedent. Thrombos. Diathes. haemorrh. (Stuttg.) 17, 307 (1967).
Hardisty, R. M., J. Margolis, The role of Hageman factor in the initiation of blood coagulation Brit. J. Haemat. 5, 203 (1959).
Horowitz. H. I., W. P. Wilcox, M. M. Fujimoto, The use of artificially depleted normal plasma for the assay of factor xi (PTA). Fed. Proc. 22, 162 (1963).
Margolis, J., Initiation of blood coagulation by glass and related surfaces. J. Physiol. 137, 95 (1957)•
Nossel, H. L., The contact phase of blood coagulation. Blackwell Scientific Publications, Oxford (1964).
Nossel, H. L., J. Niemetz, The contact product inhibitor. Clin. Res. 12, 228 (1964).
Nossel, H. L., Differential consumption of coagulation factors resulting from activation of the extrinsic (tissue thromboplastin) or the intrinsic (foreign surface contact) pathways. Blood,29, 331 (1967).
Ratnoff, D. D., An enzyme in plasma inactivating Hageman factor. J. Clin. Invest. 37, 923 (1958)•
Ratnoff, O. D., J. M. Rosenblum, Role of Hageman factor in the initiation of clotting by glass: Evidence that glass frees Hageman factor from inhibition. Amer. J. Med. 25, 160 (1958).
Ratnoff, O. D., Hageman trait. Thrombos. Diathes. haemorrh. 4, Suppl., 116 (1960).
Ratnoff, O. D., E. W. Davie, D. L. Mallet, Studies on the action of Hageman factor: Evidence that activated Hageman factor in turn activates plasma thromboplastin antecedent. J.Clin. Invest. 40, 803 (1961).
Ratnoff, O. D., J. D. Crum, Activation of Hageman factor by solutions of ellagic acid. J. lab. clin. Med. 63, 359 (1964).
Schoenmakers, J. G. G., R. M. Kurstjens, C. Haanen, F. Zilliken, Purification of activated bovine Hageman factor. Thrombos. Diathes. haemorrh. (Stuttg.) 9, 546 (1963).
Schoenmakers, J., R. Matze, C. Haanen, F. Zilliken, Proteolytic activity of purified bovine Hageman factor. Biochim. biophys. Acta (Amst.) 93, 433 (1964)•
Schoenmakers, J. G. G., Purification and properties of Hageman factor. Thesis, University of Nijmegen (1965).
Schoenmakers, J. G. G., R. Matze, C. Haanen, F. Zilliken, Hageman factor, a novel sialoglycoprotein with esterase activity. Biochem. biophys. Acta (Amst.) lof, 166 (1965).
Soulier, J. P., O. Wartelle, D. Ménaché, Caractères différentiels des facteurs Hageman et PTA; rôle du contact dans la phase initiale de la coagulation. Rev. franc. Etud. Clin. Biol. 3, 263 (1958).
Soulier, J. P., O. Wartelle, D. Ménaché, Hageman trait and PTA deficiency: The role of contact of blood with glass. Brit.J.Haemat. 5, 121 (1959).
Soulier, J. P., O. Prou-Wartelle, New data on Hageman factor and plasma thromboplastin antecedent: The role of `contact’ in the initial phase of blood coagulation. Brit. J. Haemat. 6, 88 (1960).
Speer, R. J., H. Ridgway, J. M. Hill, Activated human Hageman factor. Thrombos. Diathes. haemorrh. (Stuttg.) 14, 1 (1965)•
Vroman, L., Behavior of coagulation factors at interfaces. Biophysical mechanism in vascular homeostasis and intravascular thrombosis. p.81. Ed. P. N. Sawyer, Appleton-Century-Crofts, New York (1965).
Waaler, B. A., Contact activation in the intrinsic blood clotting system. Scand. Y. clin. lab. Invest. 11 suppl., 37 (1959).
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1969 Leiden University Press, Leiden, The Netherlands
About this chapter
Cite this chapter
Haanen, C. (1969). The Nature of the Factor IX Activating Principle. In: Hemker, H.C., Loeliger, E.A., Veltkamp, J.J. (eds) Human Blood Coagulation. Boerhaave Series for Postgraduate Medical Education, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-3423-4_12
Download citation
DOI: https://doi.org/10.1007/978-94-010-3423-4_12
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-3425-8
Online ISBN: 978-94-010-3423-4
eBook Packages: Springer Book Archive