Skip to main content
SpringerLink
Log in

The Quantitative Separation of Stacking and Self-Association Phenomena in a Dinucleoside Monophosphate by Means of NMR Concentration-Temperature Profiles: 6-N-(Dimethyl)Adenylyl- (3′,5′)-Uridine

  • Conference paper
Nuclear Magnetic Resonance Spectroscopy in Molecular Biology

Part of the book series: The Jerusalem Symposia on Quantum Chemistry and Biochemistry ((JSQC,volume 11))

Abstract

The question whether short oligonucleotides are really suitable as models for longer regions in nucleic acids has been raised (1), but will not be answered until many careful systematic studies are carried out with experimental probes at atomic resolution using nuclear magnetic resonance (NMR), supplemented with thermodynamic information from independent techniques such as UV-hypochromism and circular dichroism (CD), and guided by information on geometrical details provided by X-ray methods.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. P.N. Borer, L.S. Kan, and P.O.P. Tso, Biochemistry, 14, 4847 (1975).

    Article  CAS  Google Scholar 

  2. D.M. Gray, I. Tinoco and M.J. Chamberlin, Biopolymers, 11 1235 (1972).

    Article  CAS  Google Scholar 

  3. C. Altona, J.H. van Boom and C.A.G. Haasnoot, Eur. J. Biochemistry, 71, 557 (1976), and unpublished.

    Article  Google Scholar 

  4. H.P.M. de Leeuw and C. Altona, unpublished.

    Google Scholar 

  5. F.E. Hruska and S.S. Danyluk, J. Amer. Chem. Soc 90 3266 (1968).

    Article  CAS  Google Scholar 

  6. S.I. Chan and J.H. Nelson, J. Amer. Chem. Soc. 91 168 (1969).

    Article  CAS  Google Scholar 

  7. B.W. Bangerter and S.I. Chan, J. Amer. Chem. Soc. 91 3910 (1969).

    Article  CAS  Google Scholar 

  8. P.O.P. Ts’o, N.S. Kondo, M.P. Schweizer, and D.P. Hollis, Biochemistry, 8 997 (1969).

    Article  Google Scholar 

  9. N.S. Kondo, H.M. Holmes, L.M. Stempel, and P.O.P. Ts’o, Biochemistry, 9 3749 (1970).

    Article  Google Scholar 

  10. C. Altona and M. Sundaralingam, J. Amer. Chem. Soc., 94 8205 (1972).

    Article  CAS  Google Scholar 

  11. C. Altona and M. Sundaralingam, J. Amer. Chem. Soc., 95 2333 (1973).

    Article  CAS  Google Scholar 

  12. F.E. Evans and R.H. Sarma, J. Biol. Chem., 249 4754 (1974).

    CAS  Google Scholar 

  13. N.S. Kondo and S.S. Danyluk, J. Amer. Chem. Soc., 94 5121 (1972).

    Article  CAS  Google Scholar 

  14. C. Altona, J.H. van Boom, J.R. de Jager, H.J. Koeners, and G. van Binst, Nature, 247 558 (1974).

    Article  CAS  Google Scholar 

  15. C. Altona, H.J. Koeners, J.R. de Jager, J.H. van Boom, and G. van Binst, Rec. Trav. Chim., 93 169 (1974).

    Article  CAS  Google Scholar 

  16. C. Altona in “Structure and Conformation of Nucleic Acids and Protein-Nucleic Acid Interactions”, M. Sundaralingam and S.T. Rao, Univ. Park Press, Baltimore, p. 613 (1975).

    Google Scholar 

  17. F.E. Evans, C.H. Lee, and R.H. Sarma, Biochem. Biophys. Res. Commun., 63, 106 (1975).

    Article  CAS  Google Scholar 

  18. C.H. Lee, F.E. Evans, and R.H. Sarma, FEBS Lett., 51 73 (1975).

    Article  CAS  Google Scholar 

  19. N.S. Kondo and S.S. Danyluk, Biochemistry, 15 756 (1976).

    Article  CAS  Google Scholar 

  20. C.H. Lee, F.S. Ezra, N.S. Kondo, R.H. Sarma, and S.S. Danyluk, Biochemistry, 15 3627 (1976).

    Article  CAS  Google Scholar 

  21. F.S. Ezra, C.H. Lee, N.S. Kondo, S.S. Danyluk, and R.H. Sarma, Biochemistry, 16 1977 (1977).

    Article  CAS  Google Scholar 

  22. H. Singh, M.H. Herbut, C.H. Lee, and R.H. Sarma, Biopolymers, 15 2167 (1976).

    Article  CAS  Google Scholar 

  23. D.M. Cheng and R.H. Sarma, Biopolymers, 16 1687 (1977).

    Article  CAS  Google Scholar 

  24. C.H. Lee and I. Tinoco, Biochemistry, 16 5403 (1977).

    Article  CAS  Google Scholar 

  25. J.T. Powell, E.G. Richards, and W.B. Gratzer, Biopolymers, 11 235 (1972).

    Article  CAS  Google Scholar 

  26. J. Brahms, J.C. Maurizot, and A.M. Michelson, J. Mol. Biol. 25 481 (1967).

    Article  CAS  Google Scholar 

  27. D. Perahia, B. Pullman, D. Vasilesca, R. Cornillon, and H. Broch, Biochim. Biophys. Acta, 478 244 (1977).

    CAS  Google Scholar 

  28. C. Giessner-Prettre, B. Pullman, P.N. Borer, L.S. Kan and P.O.P. Ts’o, Biopolymers, 15 2277 (1976).

    Article  CAS  Google Scholar 

  29. P.O.P. Ts’o in “Basic Principles in Nucleic Acid Chemistry”, vol. 1 chap. 6, vol. 2 chap. 5, Acad. Press, New York (1974).

    Google Scholar 

  30. A. de Marco and K. Wühthrich, J. Magn. Res. 24 201 (1976).

    Google Scholar 

  31. A.J. Hartel and C. Altona, unpublished.

    Google Scholar 

  32. K.G. Wagner and R. Lawaczeck, J. Magn. Res., 8 164 (1972).

    CAS  Google Scholar 

  33. Y-F Lam and G. Kotowycz, Canad. J. Chem. 55 3620 (1977).

    Article  CAS  Google Scholar 

  34. C.A.G. Haasnoot and C. Altona, unpublished.

    Google Scholar 

  35. T.D. Son and C. Chachaty, Biochim. Biophys. Acta 335 1 (1973).

    Google Scholar 

  36. M. Remin and D. Shugar, Biochem. Biophys. Commun., 48, 636 (1972).

    Article  CAS  Google Scholar 

  37. C. Giessner-Prettre and B. Pullman, J. Theor. Biol. 65 189 (1977).

    Article  CAS  Google Scholar 

  38. J.L. Alderfer and P.O.P. Ts’o, Biochemistry, 16 2410 (1977).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Organic Chemistry, Gorlaeus Laboratories of the University, Wassenaarseweg 76, Leiden, Netherlands

    C. Altona, A. J. Hartel, C. S. M. Olsthoorn, H. P. M. de Leeuw & C. A. G. Haasnoot

Authors
  1. C. Altona
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. J. Hartel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. S. M. Olsthoorn
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. P. M. de Leeuw
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C. A. G. Haasnoot
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut de Biologie Physico-Chimique (Fondation Edmond de Rothschild), Université Pierre et Marie Curie (Paris VI), Paris, France

    Bernard Pullman

Rights and permissions

Reprints and permissions

Copyright information

© 1978 D. Reidel Publishing Company, Dordrecht, Holland

About this paper

Cite this paper

Altona, C., Hartel, A.J., Olsthoorn, C.S.M., de Leeuw, H.P.M., Haasnoot, C.A.G. (1978). The Quantitative Separation of Stacking and Self-Association Phenomena in a Dinucleoside Monophosphate by Means of NMR Concentration-Temperature Profiles: 6-N-(Dimethyl)Adenylyl- (3′,5′)-Uridine. In: Pullman, B. (eds) Nuclear Magnetic Resonance Spectroscopy in Molecular Biology. The Jerusalem Symposia on Quantum Chemistry and Biochemistry, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9882-7_7

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-9882-7_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-9884-1

  • Online ISBN: 978-94-009-9882-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation