Abstract
We are exploring the role of major genes in the pathogenesis of common diseases [1]. The role of heredity in control of blood pressure is evidenced by familial aggregations of blood pressure levels [2]. Correlations of systolic (S) and diastolic (D) blood pressure in identical twins (S: .55, D: .58) are significantly higher than among unidentical twins (S: .25, D: .27) [3]. Adoption studies suggest more resemblance between biologic sibs and their parents than between adopted sibs and their adoptive parents, suggesting that genetic factors rather than a common environment alone account for the familial aggregation of blood pressure levels [4].
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© 1984 Martinus Nijhoff Publishers, Boston
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Burke, W., Hornung, S., Copeland, B.R., Furlong, C.E., Motulsky, A.G. (1984). Red Cell Sodium-Lithium Countertransport in Hypertension. In: Villarreal, H., Sambhi, M.P. (eds) Topics in Pathophysiology of Hypertension. Developments in Cardiovascular Medicine, vol 30. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-6741-0_9
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DOI: https://doi.org/10.1007/978-94-009-6741-0_9
Publisher Name: Springer, Dordrecht
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