Abstract
The development of positron emission tomography (PET) is of great interest in the study of psychiatric disorders. In comparison with other functional imaging techniques PET has a better resolution and makes it also possible to study both cortical and subcortical structures three dimensionally. Of the psychiatric disorders, schizophrenia has attracted the most interest. The main reason for this are the character of the disease like disturbed thinking, hallucinations, delusions and the development of social incapability and the number of neurobiological disturbances found in the patients.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alfredsson, G., Härnryd, C. and Wiesel, F.-A. 1985. Effects of sulpiride and chlorpromazine on autistic and positive psychotic symptoms in schizophrenic patients - relationship to drug concentration. Psychopharmacol., 85, 8–13.
Asberg, M., Montgomery, S., Perris, C., et al. 1978. CPRS- The psychopathological rating scale. Acta Psychiat. Scand., Suppl. 271, 5–27.
Bergström, M., Boethius, J., Eriksson, L., et al. 1981. Head fixation device for reproducible position alignment in transmission CT and positron emission tomography. J. Comput. Assist. Tomogr., 5, 136–141.
Blomqvist, G. 1984. On the construction of functional maps in positron emission tomography. J. Cereb. Blood Flow Metab., 4, 629–632.
Blomqvist, G., Bergström, K., Bergström, M., et al. 1985. Models for 11-C-glucose. In: “Metabolism of the Human Brain Studied with Positron Emission Tomography” (Eds. T. Greitz, D.H. Ingvar and L. Widen). (Raven Press, New York), pp. 185–194.
Buchsbaum, M.S., Ingvar, D.H., Kessle, R., et al. 1982. Cerebral glucography with positron tomography. Arch. Gen. Psychiat., 39, 251–259.
Farkas, T., Wolf, A.O., Jaeger, J., et al. 1984. Regional brain glucose metabolism in chronic schizophrenia. Arch. Gen. Psychiat., 41, 293–300.
Gur, R.E., Gur, R.C., Skolnick, B.E., et al. 1985. Brain function in psychiatric disorders. Arch. Gen. Psychiat., 42, 329–334.
Ingvar, D.H. 1979. “Hyperfrontal” distribution of cerebral grey matter flow in resting wakefulness: On the functional anatomy of the conscious state. Acta Neurol. Scand., 60, 12–25.
Ingvar, D.H. and Franzen, G. 1974. Abnormalities of cerebral blood flow distribution in patients with chronic schizophrenia. Acta Psychiat. Scand., 50, 425–462.
Montgomery, S. and Asberg, M. 1979. A new depression scale designed to be sensitive to change. Br. J. Psychiat., 134, 382–389.
Nilsson, J.L.G., Stone-Elander, S., Ehrin, E., et al. 1985. 11-C-labelled compounds for the study of cerebral blood volume, blood flow and energy metabolism. In: “Metabolism of the Human Brain Studied with Positron Emission Tomography” (Eds. T. Greitz, D.H. Ingvar and L. Widen). (Raven Press, New York), pp. 107–112
Sheppard, G., Manchanda, R., Gruzelier, J. et al. 1983. 15–0 positron emission tomographic scanning in predominantly never-treated acute schizophrenic Sheppard patients. Lancet, 24/31, 1448–1452.
Spitzer, R.L. and Endicott, J. 1977. Schedule for affective, disorder and schizophrenia (SADS) 3rd edition. New York State Psychiatric Inst., Biometrics Res. New York.
Wolkin, A., Jaeger, J., Brodie, J.D., et al. 1985. Persistence of cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography. Am. J. Psychiat., 142, 564–571.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 ECSC, EEC, EAEC, Brussels-Luxembourg
About this chapter
Cite this chapter
Wiesel, FA., Wik, G., Sjögren, I., Blomqvist, G., Greitz, T., Stone-Elander, S. (1987). Regional Brain Metabolism in Drugfree Schizophrenic Patients as Measured by Positron Emission Tomography. In: Heiss, WD., Pawlik, G., Herholz, K., Wienhard, K. (eds) Clinical efficacy of positron emission tomography. Developments in Nuclear Medicine, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3345-3_19
Download citation
DOI: https://doi.org/10.1007/978-94-009-3345-3_19
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8002-6
Online ISBN: 978-94-009-3345-3
eBook Packages: Springer Book Archive