Abstract
The Increased use of small-volume infusions, continuous infusions, and individualized home care infusions in various container materials has necessitated the determination of stability and compatibility of cancer chemotherapy agents under these diverse conditions. The lack of such data can potentially lead to underdosing or administration of toxic degradation products. Because these interactions are a direct result of medication preparation, the establishment of a pharmacy-based infusion service is essential to the delivery of effective infusion therapy. Other rationale for a pharmacy-based infusion service include sterility and accuracy of drug preparaltion; central location for drug preparation and record-keeping; reduced expos:ure of other hospital personnel to cytotoxic agents; and expert knowledge of drugs, doses, fluids, and potential hazards.
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© 1987 Precept Press, Inc.
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Benvenuto, J.A., Adams, S.C., Vyas, H.M., Anderson, R.W. (1987). Pharmaceutical Issues in Infusion Chemotherapy Stability and Compatibility. In: Cancer Chemotherapy by Infusion. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3193-0_7
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DOI: https://doi.org/10.1007/978-94-009-3193-0_7
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7932-7
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