Abstract
The relative losses in foveal sensitivity of an M ‘green’, pi-4 and an S ‘blue’, pi-1 cone pathway, at different levels of adaptation, were compared in patients with RP and diabetes. Although a preferential loss in sensitivity of an S cone pathway was found for both disease groups, a more selective effect on the S cone pathway was found for diabetes. The effects of adaptation on sensitivity losses of the M cone pathway were also assessed and the losses were found to be dependent on the level of adaptation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adams, A. J., Schefrin, B. E. and Huie, K. E. A new clinical color threshold test for eye disease. Am. J. Optom. Physiol. Optics 64: 29 (1987a).
Adams, A. J., Zisman, F., Ai, E. and Bresnick, G. Macular edema reduces B cone sensitivity in diabetics. Appl. Optics 26: 1455–1457 (1987b).
Bone, R. A. and Sparrock, J. M. B. Comparison of macular pigment densities in human eyes. Vision Res. 11: 1057–1064 (1971).
Greenstein, V. C. and Hood, D. C. Test of the decreased responsiveness hypothesis in retinitis pigmentosa. Am. J. Optom. Physiol. Optics 63: 22–27 (1986).
Hood, D. C, Benimoff, N. I. and Greenstein, V. C. The response range of the blue-cone pathways: A source of vulnerability to disease. Invest. Ophthalmol. Vis. Sci. 25: 864–867(1984).
Hood, D. C. and Greenstein, V. C. Blue (S) cone pathway vulnerability: A test of a fragile receptor hypothesis. Appl. Optics 27: 1025–1029 (1988).
King-Smith, P. E., Kranda, K. and Wood, I. C. J.: An acquired color defect of the opponent-color system. Invest. Ophthalmol. 15: 584–587 (1976).
Klein, D. E. K., Davis, M. D., Segal, P., Long, J. A., Harris, A., Haug, G. A., Magli, Y. L. and Syrjala, S. Diabetic retinopathy assessment of severity and progression. Ophthalmology 91: 10–17 (1984).
Marré, M. Clinical examination of the three color vision mechanisms in acquired color vision defects. Mod. Probl. Ophthalmol. 11: 224–227 (1972).
Marré, E. and Marré, M. The influence of the three color vision mechanisms on the spectral sensitivity of the fovea. Mod. Probl. Ophthalmol. 11: 219–223 (1972).
Sandberg, M. A. and Berson, E. H. Blue and green cone mechanisms in retinitis pigmentosa. Invest. Ophthalmol. Vis. Sci. 16: 149–157 (1977).
Smith, V. C, Pokorny, J. and Starr, S. J. Variability of color mixture data 1. Interobserver variability in the unit co-ordinates. Vision Res. 16: 1087–94 (1976).
Stiles, W. S. Separation of the ‘blue’ and ‘green’ mechanisms of foveal vision by measurements of increment thresholds. Proc. Roy. Soc. B133: 96–112 (1946).
Young, R. S. L. Early-stage abnormality of foveal pi mechanisms in a patient with retinitis pigmentosa. J. Opt. Soc. Am. 72: 1021–1025 (1982).
Zwas, F., Weiss, H. and McKinnon, P. Spectral sensitivity measurements in early diabetic retinopathy. Ophthalmic Res. 12: 87–96 (1980).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Kluwer Academic Publishers, Dordrecht
About this chapter
Cite this chapter
Greenstein, V.C., Hood, D.C., Carr, R.E. (1989). A Comparison of S Cone Pathway Sensitivity Loss in Patients with Diabetes and Retinitis Pigmentosa. In: Drum, B., Verriest, G. (eds) Colour Vision Deficiencies IX. Documenta Ophthalmologica Proceedings Series, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2695-0_28
Download citation
DOI: https://doi.org/10.1007/978-94-009-2695-0_28
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7715-6
Online ISBN: 978-94-009-2695-0
eBook Packages: Springer Book Archive