Summary
In this paper we discuss three-dimensional reconstruction and flow measurements of the coronary artery vascular bed from multiple view coronary angiography. The reconstruction generates densitometric centerline and cross-sectional area measurements of the major branches of the arterial bed from two view ECG correlated digital angiograms for all images obtained throughout the cardiac cycle. The completeness of the reconstruction is well suited to allow computation of absolute flow through the major branches.
The arterial bed is represented as a branching tree structure. A projected structure including vessel branching and other recognizable node points is specificed on all images of both views. Dynamic programming with subsequent operator verification is used to determine the true vessel centerline and projected cross section in each image of each view. Each pair of computer determined structures is used to generate a three-dimensional representation of the arterial bed centerlines. The conversion factor between digital density value and vessel thickness is obtained from an average of all vessel profile measurements after correction for orientation and magnification. Segments which are too steeply inclined for orientation correction or which overlap other segments are not included in the averaging process. Absolute lumen area is then obtained from the densitometric profiles. Absolute flow measurements are obtained by tracking the leading edge of the iodine bolus down the known volume of the arterial tree.
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References
Brown BG, Bolson E, Frimer M, Dodge HT: Quantitative coronary arteriography. Estimation of dimensions, hemodynamic resistance, and atheroma mass of coronary artery lesions using the arteriogram and digital computation. Circulation 55 (2): 329–337, 1977.
Sandor T, Spears JR, Paulin S: Densitometric determination of changes in the dimensions of coronary arteries. SPIE 314: 263–272, 1981.
Spears JR, Sandor T, Als AV, Malagold M, Markis JE, Grossman W, Serur JR, Paulin S: Computerized image analysis for quantitative measurement of vessel diameter from cineangiograms. Circulation 68 (2): 453–461, 1983.
Brown BG, Petersen RB, Pierce CD, Bolson EL, Dodge HT: Arteriographic assessment of coronary disease: advantages, limitations, and clinical uses of a computer-assisted method. In: Cardiology Update, Reviews for Physicians, Elsevier Biomedical, New York, 1983, pp 67–98.
Doriot P-A, Rasoamanambelo L, Honegger H-P, Wrier G, Bopp P, Rutishauser W: Measurement of the degree of coronary stenosis by digital densitometry. Comput Cardiol, 329–332, 1981.
Nichols AB, Gabrieli CFO, Fenoglio JJ, Esser Jr PD: Quantification of relative coronary arterial stenosis by cinevideodensitometric analysis of coronary arteriograms. Circulation 69 (3): 512–522, 1984.
Kruger RA: Estimation of the diameter of and iodine concentration within blood vessels using digital radiography devices. Med Phys 8 (5): 652–658, 1981.
Reiber JHC, Gerbrands JJ, Booman F, Troost GJ, Boer A den, Slager CJ, Schuurbiers JCH: Objective characterization of coronary obstructions from monoplane cineangiograms and three-dimensional reconstruction of an arterial segment from two orthogonal views. In: Schwartz MD (ed): Applications of Computers in Medicine, 1982, pp 93–100.
Reiber JHC, Slager CJ, Schuurbiers JCH, Boer A den, Gerbrands JJ,.Troost GJ, Scholts B, Kooijman CJ, Serruys PW: Transfer functions of the X-ray-tine-video chain applied to digital processing of coronary cineangiograms. In: Heintzen PH, Brennecke R, (eds): Digital Imaging in Cardiovascular Radiology. Georg Thieme Verlag, Stuttgart, 1983, pp. 89–104.
Reiber JHC, Kooijman CJ, Slager CJ, Gerbrands JJ, Schuurbiers JCH, Boer A den, Wijns W, Serruys PW: Computer assisted analysis of the severity of obstructions from coronary cineangiograms: a methodological review. Automedica 5: 219–238, 1984.
Parker DL, Pope DL, White KS, Tarbox LR, Marshall HW: Three dimensional reconstruction of vascular beds. In: Bacharach SL (ed): Proc Information Processing in Medical Imaging, Martinus Nijhoff Publishers, Dordrecht/Boston/Lancaster, 1985, pp. 414–430.
Parker DL, Pope DL, Van Bree R, Desai R: Three dimensional reconstruction of vascular beds from digital angiographic projections. Intrnl Workshop on Physics and Eng in Comp Multi-dimensional imaging and processing, Newport Beach, CA, 1986 (in press).
Parker DL, Pople DL, van Bree RE, Marshall HW: Flow measurements from 3D reconstruction of moving arterial beds from digital subtraction angiography. Comput Cardiol, 1986 (in press).
Parker DL, Pope DL, van Bree R, Marshall HW: Three dimensional reconstruction of moving arterial beds from digital subtraction angiography. Comput Biomed Res, 1987 (in press).
Parker DL, Pope DL, van Bree RE, Marshall HW: Three dimensional reconstruction and cross section measurements of coronary arteries using ECG correlated digital coronary arteriography. In: Heintzen PH (ed): Progress in Digital Angiocardiography. Martinus Nijhoff Publishers, Dordrecht, 1987 (in press).
Parker DL, Pope DL, van Bree RE, Marshall HW: Blood flow measurements in digital cardiac angiography using 3D coronary artery reconstructions. In: Heintzen PH (ed): Progress in Digital Angiocardiography. Martinus Nijhoff Publishers, Dordrecht, 1987 (in press).
MacKay SA, Potel MJ, Rubin JM: Graphics methods for tracking three-dimensional heart wall motion. Comp Biomed Res 15: 455–473, 1982.
Garrison JB, Ebert WL, Jenkins RE, Yionoulis SM, Malcom H, Heyler GA: Measurement of three-dimensional positions and motions of larger numbers of spherical radiopaque markers from biplane cineradiograms. Comput Biomed Res 15: 76–96, 1982.
Potel MJ, MacKay SA, Rubin JM, Aisen AM, Sayre RE: Three-dimensional left ventricular wall motion in man. Coordinate systems for representing wall movement direction. Invest Radiol 19 (6): 499–509, 1984.
Kim HC, Min BG, Lee TS, Lee SJ, Lee CW, Park JH, Han MC: Three-dimensional digital subtraction angiography. IEEE Trans Med. Imaging MI-1(2): 152–158, 1982.
Colchester ACF, Hawkes DJ, Brunt JNH, Du Boulay GH, Wallis A: Pulsatile blood flow measurements with the aid of 3-D reconstructions from dynamic angiographie recordings. In: Bacharach SL (ed): Proc Information Processing in Medical Imaging, Martinus Nijhoff Publishers, Dordrecht/Boston/Lancaster, 1986: pp 247–265.
Reiber JHC, Gerbrands JJ, Troost GJ, Kooijman CJ, Slump CH: 3-D reconstruction of coronary arterial segments from two projections. In: Heintzen PH, Brennecke R (eds): Digital Imaging and Cardiovascular Radiology, Georg Thieme Verlag, Stuttgart, 1983, pp 151–163.
Mol CR, Colchester ACF, Hawkes DJ, O’Laoire SA, Hart G: 3-D reconstruction from biplane X-ray recordings: application to arterio-venous malformations. In: Jordan MM, Perkins WJ (ed): Computer-Aided Biomedical Imaging and Graphics. London: Biol Engin Soc, 1984 (abstract).
Pope DL, Parker DL, Gustafson DE, Clayton PD: Dynamic search algorithms in left ventricular border recognition and analysis of coronary arteries. Comput Cardiol, 71–75, 1984.
Pope DL, Parker DL, Clayton PD, Gustafson DE: Left ventricular border recognition using a dynamic search algorithm. Radiology 155: 513–518, 1985.
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Parker, D.L., Wu, J., Pope, D.L., Van Bree, R., Caputo, G.R., Marshall, H.W. (1988). Three-dimensional reconstruction and flow measurements of coronary arteries using multi-view digital angiography. In: Reiber, J.H.C., Serruys, P.W. (eds) New Developments in Quantitative Coronary Arteriography. Developments in Cardiovascular Medicine, vol 87. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1309-7_14
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DOI: https://doi.org/10.1007/978-94-009-1309-7_14
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